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CV PHARM...Antihypertensives > Adrenergic Neuron Blockers > Flashcards

Adrenergic Neuron Blockers Flashcards

1
Q

Reserpine MOA

A 
Inhibits VMAT (uptake 2)
Depletes NE and 5-HT from neurons

Decreased sympathetic tone reduces TPR, CO, renin release, BP

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2
Q

Reserpine clinical uses

A

oral

mild to moderate HTN

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3
Q

Reserpine side effects

A

CNS effects (sedation and mental depression)
gastric and duodenal ulcers
Shouldn’t be used in pts w/ Hx of depression

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CV PHARM...Antihypertensives (11 decks)

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