Common Congenital Infections

Question 1

Transplacental; 1° infection via consumption of raw meat or contact with cat feces.

Answer 1

Toxoplasmosis

Question 2

Hydrocephalus. Intracranial calcific tions. Chorioretinitis. Ring-enhancing lesions on MRI.

Answer 2

Toxoplasmosis

Question 3

Treatment for Toxoplasmosis

Answer 3

Pyrimethamine + sulfadiazine.

Question 4

Purpuric “blueberry muf n” rash. Cataracts. Mental retardation. Hearing loss. PDA.

Answer 4

Rubella

Question 5

Petechial rash. Periventricular calcifications.

Answer 5

CMV

Question 6

Treatment for CMV

Answer 6

Postpartum ganciclovir.

Question 7

Skin, eye, and mouth infections. Life-threatening CNS/systemic infection.

Answer 7

HSV

Question 8

Infection with HSV

Answer 8

Perform a C-section if lesions are present at delivery.

Question 9

Maculopapular skin rash. Lymphadenopathy. Hepatomegaly. “Snuffles”: mucopurulent rhinitis. Osteitis. Late congenital syphilis: Saber shins. Saddle nose. CNS involvement. Hutchinson triad: peg-shaped central incisors, deafness, interstitial keratitis.

Answer 9

Syphilis

Question 10

Treatment for syphilis

Answer 10

Pen G