typhoid fever Flashcards
1
Q
where is typhoid common?
A
developing nations in South East Asia, Southern and Central America.
2
Q
how does typhoid present?
A
sustained fever, anorexia, malaise, vague abdominal discomfort, constipation or diarrhea, dry cough.
3
Q
what can be seen on examination of a patient with TF?
A
Pulse-temperature dissociation, hepatosplenomegaly, Rose spots (30-50% of patients, but may disappear before presentation)
4
Q
how is typhoid diagnosed?
A
isolation of the organism in cultures of blood (80% if 2 cultures taken), stool, urine, bone marrow, and duodenal aspirates.
5
Q
how is typhoid treated?
A
IV Ceftriaxone 2g OD (empirical)
Once sensitivities known, can switch to PO Ciprofloxacin 500mg BD, or PO Azithromycin 500mg OD.
