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Obstetrics > Autoimmune Disorders > Flashcards

Autoimmune Disorders Flashcards

1
Q

What percentage of RA patients symptoms improve in pregnancy?

A

80 - 90%

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2
Q

What percentage of RA patients usually relapse post partum and by what time point post partum?

A

75% relapse within 3 months postartum

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3
Q

What is the effect of RA on pregnancy?

A

No adverse affects

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4
Q

True or false: It is safe to continue TNF alpha blockers (infliximab, adalumumab ect) in pregnancy

A

True

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5
Q

What should happen to the infant in a mom treated with TNF alpha blocker

A

delay rotovirus live vaccine for 6 months following delivery

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6
Q

True or false: Methotrexate should be stopped in pregnancy

A

True

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7
Q

What is the drug of choice in pregnancy for RA?

A

Prednisone

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8
Q

How many diagnostic criteria are needed to diagnose lupus erythematosus?

A

4 criteria

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9
Q

What is the renal protein excretion cutoff required to diagnose lupus?

A

> 500 mg/24hr urine protein

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10
Q

What are the maternal risks associated with Lupus Nephritis?

A

Exacerbation, Nephritis, PreEclampsia

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11
Q

What are the fetal risks associated with Lupus?

A

SAB, IUFD, FGR, PTB, PPROM, Heart block

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12
Q

IUFD with Lupus Erythematosus is strongly associates with what?

A

Presence of antiphospholipid antibodies

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13
Q

What serologies should be obtained in early pregnancy?

A

Anti SSA-SSB

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14
Q

What should be done if SSA, SSB positive?

A

Fetal echocardiogram in the 2nd trimester

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15
Q

How often and when should you start fetal surveillance in a patient with Lupus?

A

twice weekly starting at 28 weeks

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16
Q

When and how often should you measure fetal growth in patients with Lupus?

A

q 4 weeks after 20 weeks

17
Q

What is the drug of choice to treat lupus during pregnancy?

A

Hydroxychloroquine

18
Q

What do patients treated with high dose steroids for Lupus need in labor?

A

100 mg IV q 8 in labor and for 24 hrs post partum

19
Q

Which maternal antibody is most related to neonatal lupus?

A

SSA/SSB antibodies

Obstetrics (28 decks)

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