9/24 Flashcards
Endocrine system
Hormone:chemical secreted by endocrine gland
Major hormone producing glands:pituitary, gonads, thyroid, parathyroid, adrenals, pancreas
Hypothalamus:
releases gonadotropin hormone (Gn-Rh)
Part of limbic system in brain, helps to regulate basic motivations
The four f’s (basic motivations):
Fighting
Feeding
Fleeing
Sexual behavior
Hypothalamus control
Pituitary gland: follicle stimulating hormone (FSH) + luteinizing hormone (LH)
Anterior lobe interacts with gonads
Gonads:
steroids (estrogen, progesterone, testosterone)
Adrenal gland:
estrogen and testosterone
FSH (follicle stimulating hormone)
People with ovaries: maturation of ovarian follicles
People with testes: growth of sperm cells
FSH controls sperm production in males
LH(luteinizing hormone)
People with ovaries:ovulation, development of corpus luteum
People with testes: production of testerone
LH controls testosterone production in male
ovum development and estrogen secretion in females
Testes
Produce androgens (ie T)
Development and maintenance of masculine physical characteristics
Maintaining genital and ability to produce sperm
Growth of bone and muscle
Hypothalamic-pituitary-gonadal axis
neg feedback loop
maintains a steady level of testosterone
hypothalamus-GnRH->pituitary gland- FSH(sperm) & LH (production of testosterone) -> Testes-testosterone and inhibin
When T is lower, this signals hypothalamic pituitary gonadal axis to start
Assumptions that testosterone levels are fairly steady
Research evidence: there are some fluctuations in T
Higher T in morning, lower T at night
Weekly fluctuations
Seasonal fluctuations (LOWER IN summer higher in fall)
T can be affected by behavior (sexual activity can be associated with T)
Cortisol level decrease T
Estrogen:
Development of physical characteristics (stimulate growth of uterus, pelvis, breast )
Stopping growth of bone and muscle (stop growing when we get our period)
Regulation of menstrual cycle
Maintaining mucous membranes of vagina
Progesterone
Regulation of menstrual cycle
Development of uterine lining
Inhibin
Involved in helping regulating the hormones and neg feedback loop (too low levels)
Pituitary gland (in people with ovaries)
Prolactin: milk production, progesterone production
High levels of prolactin in people with testes= sexual desire difficulty, erectile difficulties
Oxytocin (tend and befriend;social bonding)
Milk secretion, contractions of uterus during childbirth
Hypothalamic-pituitary-gonadal axis in people with ovary:
Hypothalamus (GnRH)->pituitary gland (FSH & LH)->Ovaries-ESTROGEN,PROGESTERONE, INHIBIN
Hypothalamus detected levels of estrogen and progesterone and releases them according to neg or pos level
Female and Male hypothalamic pituitary gonadal axis are quite similar
Menstruation
shedding of endometrium (layer of uterus)-no fertilization of ovum
Menarche
first menstruation
Amenorrhea
absence of menstruation
Primary amenorrhea: never had period
Secondary amenorrhea: was having period then stopped
~~You can still get pregnant even having amenorrhea
Menstrual cycle
Regulated by fluctuating hormones
Length: 21-36 days
4 phases
4 phases of menstrual cycle
1)follicular (prolifertaive phase) (10 days)
2)ovulatory phase
3)luteal phase (14 days)
4)menstrual phase
Hormonal Birth Control
The combination pill (estrogen and synthetic progesterone)
Hormones for 21 days, then no pill or sugar pill for 7 days
Pill works by preventing ovulation
You have constant higher dose of estrogen and progesterone and maintaining consistent hormone levels then what is expected
This throws off the negative feedback loop (stops body from producing natural hormones)
Also helps thicken cervical mucous
Pill maintains more consistent hormone levels (ie no peak in estrogen, no ovulation)
What are recent advancement in male birth control
One option is a pill increases progesterone to decrease sperm levels but this also lowers T levels
~Participants will report acne, headaches, ED, weight gain, etc.. (which is why participants drop out)
Another advancement is a nonsurgical vasectomy created in india(a gel injected to testes)
Dysmenorrhea
Pain or discomfort (cramps)
fluid retention(bloating)
~mastalgia is bloating in breasts
primary dysmenorrhea: just normal period cramps
secondary dysmenorrhea:pain associated with organic problems
where do cramps come from
prostaglandins (cuts off blood flow)