9. Dengue fever Flashcards

1
Q

Which organism causes dengue fever?

A

Dengue virus (most common arbovirus, 4 serotypes)

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2
Q

Where is dengue fever endemic?

A

Africa, Asia, Indian SC

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3
Q

How is dengue virus transmitted?

A

Aedes aegypti mosquito

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4
Q

Which investigations indicate dengue fever?

A

Investigations usually normal

Diagnosed via dengue PCR and dengue serology (IgM)

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5
Q

What is the incubation period for dengue fever?

A

3-14 days

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6
Q

What are the signs and symptoms of dengue fever?

A

1st infection ranges from asymptomatic to severe febrile illness. symptoms last 1-5 days and improves 3-4 days after rash

Symptoms:
1. headache and myalgia

Signs:

  1. fever
  2. widespread maculopapular rash
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7
Q

How is 1st infection with dengue fever treated?

A

supportive only

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8
Q

What does re-infection with a different dengue virus serotype cause?

A

antibody-dependent enhancement:

  1. dengue haemorrhagic fever
  2. dengue shock syndrome (with non-blanching petechial rash)
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