9 - Fungal infection Flashcards Preview

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Flashcards in 9 - Fungal infection Deck (13):
1

Are fungi eukaryotes or prokaryotes?

eukaryotes

NOTE: they have a similar metabolism to humans

2

Which of the 2 phyla make up 90% of all human fungal infections?

ascomycetes

3

What do basidiomycetes make up?

mushrooms

4

How do fungi digest their food?

What is the collective name for organisms that do this?

(extracellularly)
- they produce hydrolytic enzymes which are pumped out into the environment
- they (are powerful polymer degrading substances which) rot the material around them
- so the fungus us effectively suspended in its food sourc

SAPROPHYTES

5

Give some examples of fungal allergies that result due to inhalation of fungal spores?

- rhinitis
- dermatitis
- asthma
- ABPA (allergic broncho-pulmonary aspergillosis)

6

List some symptoms of mycotoxicoses

- breathing problems
- dizziness
- severe vomiting
- diarrhoea
- dehydration
- hepatic and renal failure (6 days later)

7

What is the treatment for mycotoxicoses?

- gastric lavage (wash out toxins)
- liver transplant

8

What are the classifications of fungi based on the level of tissue they affect (i.e. the four types of mycoses)?

superficial
cutaneous
subcutaneous
systemic

9

Why are cutaneous mycosis given the name Tinea?

latin for worm
caused by worm-like parasites

10

What is a mycetoma?

a type of subcutaneous mycosis
a chronic infection of the skin, subcutaneous tissue ands sometimes bone. Characterised by discharging sinuses filled with organisms.

11

What re the 2 types of deep/systemic mycoses?

primary/dimorphic - able to establish infection in a normal host
opportunistic - require a compromised host in order to establish infection

12

What type of fungal infections are Candida infections?

superficial mycosis

13

What are the methods for diagnosis of fungal infections?

- sample acquisition
- microscopy
- culture
- non-culture methods
e.g. antibody and antigen based assays can be used to detect fungal polysaccharides e.g. mannan, glucan