9 Review Flashcards
(44 cards)
ICF is the fluid inside the cell, it is maintained by the ______
Cell membrane
The ECF is split into 2 compartments
- Interstitial fluid
2. Plasma
What membrane separates the compartments of the ECF
Capillary walls
What is passive transport
Moves with gradient (H>L)
No energy needed
What are some types of passive transport
Diffusion
Facilitated diffusion
Osmosis
What is active transport
Moves against gradient (L>H)
Needs energy
What are the types of active transport
Primary and secondary
Ion channels are very specific to ____ and _____, and the flow depends on _________
Specific to ion size and charge
Flow depends on number open
Leak channels
Always open
Gated channels
Closed until a stimulus opens it
Ligand gated channel
Remains closed until proper ligand binds
Remains open as long as ligand is around, closes when it removed
Fast to elicit a cellular response
2nd messenger gated channel
Remains ope as long as 2nd messenger is around, closes when it is removed
2nd messenger i made until receptor is no longer stimulated
Slower to cause a responses more diverse effects
Voltage gated channel
Remain closed until membrane potential reaches a specific value
Remains open depending on the membrane potential and channel properties
Resting membrane potential is due to
Charge difference across cell membranes due to concentration gradients of ions
Inside of cell: _____ charge
Negative
Outside of the cell: ____ charge
Positive
What is the typical RMP of the body?
-70 mV at rest
Range is -20 to -100
What channel is the major contributor of RMP
K+ current through leak channels
Na-K ATPase is necessary for RMP.
____ Na moves ____
____ K moves ______
3 NA out
2 K in
At Rest- RMP (K flux through leak channels)
Local depol. (Stimulation occurs- ligand gated Na channels)
Threshold, -60 mV (Nav channels open)
Over shoot (Na influx)
Repol (Na slows, K rises)
Hyperpol ( more K leaves)
At rest
Know this
Synapses are
Site of communication between cells
What are the types of synapses
Electrical (gap junctions)
chemical
Electrical synapses are
Direct connections between cells that allows ions to flow between
Makes a syncytium ( bunch of cells acting as 1)
Synaptic transmission
Flow
Propagation of AP> release of NT> bonding of NT to receptor> effect on postsynaptic cells
