Immunology: HIV Flashcards

1
Q

Pathogenesis:

What is the very basic aetiology of HIV?

A
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2
Q

Epidemiology:

How many people are living with HIV and how many have died from AIDS?

A
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3
Q

Epidemiology:

How many people are infected with HIV each day?

A
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4
Q

Epidemiology:

How is HIV transmitted and how does it gain entry to cells?

A
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5
Q

Pathogenesis:

What is the innate response to HIV?

A
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6
Q

Pathogenesis:

What is the adaptive response to HIV?

A
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7
Q

Pathogenesis:

How does HIV damage the immune response?

A
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8
Q

Life cycle:

What is the life cycle of HIV?

A
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9
Q

Natural history:

What is the natural history of HIV?

A
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10
Q

Natural history:

Outline the changes in Mucosal CD4 T cells, CD4 T cell counts in blood, Viremia and Immune activation in HIV over weeks, years and months.

A
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11
Q

Diagnosis:

What is the screening test and confirmation test for HIV?

A
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12
Q

Diagnosis:

What investigations happen after diagnosis?

A
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13
Q

Treatment:

What is the current treatment of HIV?

A
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14
Q

Treatment:

What is HIV treatment in Pregnancy?

A

(Also called AZT, an NRTI that acts as a Thymidine analogue)

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15
Q

Treatment:

What are the limitations of HAART?

A
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16
Q

Treatment:

Outline the treatment diagram for HIV

A
17
Q

HIV Treatment:

What are the examples and side effects of Fusion inhibitors?

A
18
Q

HIV Treatment:

What are the examples and side effects of Attachment inhibitors?

A
19
Q

HIV Treatment:

What are the examples and side effects of Nucleoside Reverse Transcriptase inhibitors (NRTI)?

A

“DAZZLES TEC”

  • Didanosine
  • Abacavir
  • Zalcitabine
  • Zidovudine
  • Lamivudine
  • Emtricitabine
  • Stavudine
  • Trizivir
  • Epzicom
  • Combivir
20
Q

HIV Treatment:

What are the examples and side effects of Non-NRTI?

A
21
Q

HIV Treatment:

What are the examples and side effects of Integration inhibitors?

A
22
Q

HIV Treatment:

What are the examples and side effects of Protease inhibitors?

A

“FINALS RA”

  • Fosampernavir
  • Indinavir
  • Nelfinavir
  • Amprenavir
  • Lopinavir
  • Saquinavir
  • Ritonavir
  • Amprenavir
23
Q

HIV Treatment:

What are the examples and side effects of Nucleotide RTI?

A