Cancer (test 4) Flashcards

1
Q

What is cancer?

A

uncontrolled growth of normal tissue and the growth of tumours.

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2
Q

What is the difference between benign and malignant tumours?

A
B = Non-cancerous does not move 
M = cancerous can invade other cells.
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3
Q

What is a diffuse tumour?

A

Scattered throughout the body

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4
Q

What is carcinoma?

A

Cancer skin or in tissues that line or cover internal organs.

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5
Q

What is sarcoma?

A

Cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue

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6
Q

What is leukemia?

A

Cancer of the white blood cells

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7
Q

What is lymphoma?

A

Cancer of the cells in the immune system

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8
Q

What is myeloma?

A

Cancer of the B cells that produce antibodies

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9
Q

What are three treatment options for Cancer?

A

Surgery
Radiation
Chemotherapy

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10
Q

What are some side effects of antineoplastic drugs?

A

bone marrow depression
skin and GI ulceration
Hair loss

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11
Q

What are alkylating agents used for?

A

Smaller or slower growing tumours

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12
Q

How do alkylating agents work?

A

They create an irreversible cross-link in DNA interfering with the replication process.

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13
Q

What are some examples of Alkylating agents?

A

dacarbazine
oxaliplatin
busulfan
carboplatin

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14
Q

How do antimetabolites work?

A

They interfere with the metabolism of cancer cells

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15
Q

What are some examples of antimetabolites?

A

cytarabine
fluorouracil
methotrexate

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16
Q

How do topoisomerase 1 Inhibitors work?

A

Cause DNA damage in replicating cells

17
Q

What are some examples of topoisomerase 1 inhibitors?

A

irinotecan

topotecan

18
Q

How do tyrokinase inhibitors work?

A

They inhibit cellular growth and decrease proliferation of cells