Terms Flashcards

1
Q

nonmalfeasance

A

duty to do no harm

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2
Q

beneficence

A

actively promoting good

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3
Q

autonomy

A

self-determination and the ability to act on one’s own

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4
Q

justice

A

being fair or equal in one’s action

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5
Q

additive effects

A

combo of 2/+ drugs is equivalent to the sum of the individual effects if given alone
1+1=2

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6
Q

biotransformation

A

metabolism

occurs mainly in the liver and produces a metabolite that is either inactive or active

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7
Q

dependence

A

compulsive or chronic need

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8
Q

drug-induced teratogenesis

A

toxic effects of drugs cause congenital anomalies or defects

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9
Q

first-pass effect

A

initial metabolism in the liver of a drug absorbed from the GI tract

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10
Q

half-life

A

time required for half of an administered dose of drug to be eliminated by the body

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11
Q

idiosyncratic reaction

A

abnml and unexpected response that is peculiar to an indv pt

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12
Q

metabolite

A

chemical form of a drug that is the product of 1/+ metabolic rxn

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13
Q

pharmaceutics

A

preparing and dispensing drugs

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14
Q

pharmacodynamics

A

biochemical and and physiologic interactions of drugs at their site of activity
examines effect of the drug

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15
Q

pharmacoeconomics

A

economi factors impacting cost of drug therapy

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16
Q

pharmacogenomics

A

influence of genetic factors that reult in the absence, overabundance, or insufficiency of drug-metabolizing enzymes

17
Q

pharmacognosy

A

natural plant and animal sources

18
Q

pharmacokinetics

A

what happens to a drug from time to enters until parent drug and all metabolites have left the body
represents absorption, distribution, metabolism, and excretion

19
Q

pharmacology

A

drugs

20
Q

pharmacotherapeutics

A

tx of pathological cond’n

21
Q

prodrug

A

inactive drug dosage form that is converted to an active metabolite

22
Q

synergistic effects

A

combo of 2/+ drugs is greater to the sum of the individual effects if given alone
1+1>2

23
Q

therapeutic effect

A

desired effect

24
Q

therapeutic index

A

ration b/w the toxic and therapeutic concentrations

25
Q

tolerance

A

reduced response after prolonged use

26
Q

trough level

A

lowest concentration after it falls from its peak level