Neuroscience methods 1 Flashcards

1
Q

Explain Positron Emission Topography (PET)

A

A contrast is injected into the bloodstream which attaches to blood molecules that are eventually absorbed by active neurons.

We observe the active neurons that use the oxygenated blood which needs to be replenished.

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2
Q

What are the advantages of X-ray

A

You can image bone

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3
Q

What is tomography

A

Visualisation by sections through imaging which is then converted to viewable 3D volumes and 2D sections

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4
Q

What does EEG measure

A

Firing in populations of neurons

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5
Q

What are the main diagnostic uses of EEG?

A

Epilepsy and sleep disorder

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6
Q

What is the neuronal activity measured by an EEG

A

Postsynaptic potentials at the dendritic end of pyramidal neurons

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7
Q

What is the standard electrode placement

A

International 10-20 system

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8
Q

What is the Gamma range and behavioral correlate

A

30-50 Hz

Active corticial processing

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9
Q

What is the Beta range and behavioral correlate

A

13-30 Hz

Motor Activity

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10
Q

What is the Alpha range and behavioral correlate

A

8-13 Hz

Occipital region when eyes closed

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11
Q

What is the Theta range and behavioral correlate

A

4-8 Hz

Attention and memory processes

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12
Q

What is the Delta range and behavioral correlate

A

0.5-4 Hz

Sleep

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13
Q

What is the inverse problem in EEG

A

It is impossible to source the location of neural activity from an EEG measurement

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14
Q

Does EEG have good time resolution

A

Yes

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15
Q

Does EEG have good spatial resolution

A

No

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16
Q

What does a single-cell recording measure

A

Action-potential produced by individual neurons

17
Q

What is Immunocytochemistry

A

Antibodies target specific protein antigens in a cell

18
Q

What is In Situ hybridisation

A

Labels complementary DNA or RNA strand to localised specific sequence in a cell

19
Q

What is Deoxyglucose Uptake

A

Active neurons use glucose - radioactively label deoxyglucose that is taken up by neurons