Chapter 3 - E1 Flashcards

1
Q

Products of Mitosis

A

Produces 2 identical daughter somatic cells

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2
Q

What is included interphase?

A

G1, G0, S, and G2

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3
Q

Characteristic of G1?

A

High levels of gene expression

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4
Q

S (synthesis phase) characteristics

A

Where DNA replication occurs

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5
Q

G0 characteristics

A

Where cells express their genetic information and carry out normal function but do not replicate

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6
Q

G2 characteristics

A

Preparation for cell division

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7
Q

M phase substages

A

Prophase
Metaphase
Anaphase
Telophase/Cytokinesis

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8
Q

Karyokinesis

A

Equal partitioning of the chromosomal material into the nuclei of 2 daughter cells

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9
Q

Cytokinesis

A

Equal partitioning of the cytoplasmic contents into 2 daughter cells

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10
Q

Centromere

A

Specialized DNA sequence on each chromosome where sister chromatids are joined together

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11
Q

What occurs in Prophase?

A

Chromosome condensation begins
Centrosomes migrate toward opposite poles
Microtubules extend to form a partial mitotic spindle

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12
Q

What occurs in Prometaphase?

A

Centrosomes extend microtubules that attach to kinetochores of chromosome centromeres
Chromosomes move toward the middle

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13
Q

What occurs in Metaphase?

A

Chromosomes are fully condensed and are aligned so that the sister chromatids lie on either side of the metaphase plate
- Kinetochore, nonkinetochore, and astrial tubules are fully extended

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14
Q

What occurs in Anaphase?

A

Sister chromatid seperation trhgouh the breakdown of cohesin

Daughter chromosomes move toward opposite poles

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15
Q

What occurs in Telophase/Cytokinesis?

A

Cells are elongated

Cytokinesis diveds the cytoplasm to create 2 new cells

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16
Q

How to spindle fiber microtubules elongate?

A

Through the addition of tubulin subunits

17
Q

Where do the - and + ends anchor?

A
  • end anchors at the centrosome

+ end grows away from the centrosome

18
Q

What is the role of cohesin?

A

Coats sister chromatics (most concentrated near the centrosomes)
Hold the chromosomes together to reduce the pull of the kinetochore

19
Q

Definition of disjunction

A

Seperation of chromosomes

20
Q

What are the four checkpoints?

A

G1, S, G2, and Metaphase

21
Q

Products of Meiosis

A

4 haploid gametes

22
Q

Events that occur in Meiosis 1

A

Homologous chromosomes pair
Crossing over occurs
Segregation of the homologous chromosomes (reduces it to haploid number)

23
Q

Events that occur in Meiosis 2

A

Sister chromatids seperate

Produces 4 genetically distinct haploid cells

24
Q

What is SRY?

A

Sex determining region of the Y gene in human males

- inhibits femaleness

25
Q

What is a Barr Body?

A

Inactivated X chromosome when too many X’s are present

- Random X-inactivation hypothesis

26
Q

What are kinesin motor proteins?

A

Use ATP hydrolysis to physically move toward the plus end

27
Q

What are dynein motor proteins?

A

Move toward the minus end

28
Q

Role of separase

A

Cleave the cohesin complex to promote chromatid seperation

29
Q

Chiasma

A

Contact points between homologous chromosomes where recombination has already occurred

30
Q

What does TDF do?

A

Stimulates transcription of genes needed for Wolffian duct development into male reproductive tissues