Gfr Flashcards

1
Q

Filtration size

A

4 to 8 nm

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2
Q

Why protein not filternled

A
  1. Negative charge
  2. Fenestrations
  3. Small slit diaphragn
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3
Q

Integrity of slit diaphragm by?

A

Nephrin
Podosin
Alpha actinin

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4
Q

Net filtration pressure

A

Hydro(GC) - 《H(BC) + O(GC)》

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5
Q

Gold standard and mc substance to measure gfr

A

Inulin,

Creati

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6
Q

Gfr formula

A

Urine inulin conc * urine volume/ plasma inulin conc

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7
Q

Actual rpf formula

A

Estimated/0.9

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8
Q

Filtration fraction

A

Gfr/rpf

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9
Q

Subs causing vc of mesangial cell

A

Endothelin
Angiotensin 2
Nor epinephrine

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10
Q

Subs causing vd of mesangial cell

A

Camp,
Anp,
NO

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