Risk Models to Direct Treatment

Question 1

Name the two prognostic models.

Answer 1

MSKCC

IMDC

Question 2

Prognostic factors for the MSKCC model
Interval from diagnosis to treatment of \_\_\_\_\_\_\_\_\_\_\_\_\_.
Karnofsky performance status: 
LDH value:
Corrected serum calcium: 
Serum Hemoglobin:

Answer 2

Prognostic factors for the MSKCC model
Interval from diagnosis to treatment of <1 year
Karnofsky performance status: <80%
LDH value: >1.5 times the upper limit of normal
Corrected serum calcium: greater than the upper limit of normal
Serum Hemoglobin: less than the lower limit of normal

Question 3

MSKCC Prognostic risk groups:
Low:
Intermediate:
Poor:

Answer 3

MSKCC Prognostic risk groups:
Low: No risk factors
Intermediate: 1-2 risk factors
Poor: 3 or more

Question 4

IMDC prognostic factors:
Timing of diagnosis to systemic therapy
Karnofsky score
Hgb
Calcium
NEUTROPHIL
PLATELET

Answer 4

IMDC prognostic factors:
Timing of diagnosis to systemic therapy <1 year
Karnofsky score <80%
Hgb less than the lower limit of normal <120
Calcium upper limit of normal >10.2
NEUTROPHIL >7.0
PLATELET >400,000

Question 5

IMDC risk groups
Low
Intermediate
Poor

Answer 5

IMDC risk groups
Low NO RISK FACTORS
Intermediate 1-2
Poor 3 OR MORE