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PLE Review CARDS by CHA > Physio > Flashcards

Physio Flashcards

1
Q

Normal Nerve RMP (TN handout)

A

-70mV

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2
Q

N activation gate
Na inward current
“ON”
(TN handout)

A

Depolarization

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3
Q

Closure of Na inactivation gatr
Stop Na inward
K outward current
“OFF”

A

Repolarization(TN handout)

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4
Q

Tissue macrophage (Nervous system)

A

Microglia (TN handout)

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5
Q

Forms Myelin

A

CNS: Oligodendrocytes
PNS: Schwann Cells
(TN handout)

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6
Q

Envelop synapses

Form BBB

A

ASTROCYTes
Fibrous astrocyte - white matter
Protoplasmic aatrocytes - gray matter
(TN handout)

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7
Q

ACtion potential starts?

A

Axon hillock/initial segment

TN handout

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8
Q

Autoimmune disease
Paraperesis, optic neuritis, paresthesia
Exacerbated by inc temp

A

Multiple sclerosis
Relapsing-remitting or primary progressive
(TN handout)

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9
Q

Increase in Na Conductance

NA INFLUX

A 
Endplate Potential (Skeletal.Ms endplate)
(TN handout)
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10
Q

Cl influx
K efflux
Closure of Na or Ca Channels

A

FAST Inhibitory Post Synaptic Potential (IPSP)

TN handout

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11
Q

Na Influx

Ca influx

A

FAST Excitatory postsynaptic Potential

TN handout

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12
Q

Slow K efflux

A

SLOW ExCitatory Postsynaptic Potential

TN handout

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13
Q

K efflux

A 
Presynaptic Inhibition
(TN handout)
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14
Q

Brain Main INHIBITORY NT

A

GABA

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15
Q

BRAIN MAIN EXCITATORY NT

A

Glutamate

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16
Q

Spinal Cord MAIN INHIBITORY NT

A

Glycine

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17
Q

Utilize 2nd messengers like IP3/DAG or cAMP

GABA B, neurokinin receptor, opioid receptor

A

G Protein Coupled Receptors

18
Q

Ion channel linked receptors

GABA A, Nicotinic, NMDA, Glycine, ANP, 5HT3 receptors

A

INOTROPIC RECEPTORS

19
Q

Opioid Peptide receptors:

  • Analgesia, diuresis, sedation, meiosis, dysphoria
  • Enk> End & Dyno
A

KAPPA

20
Q

Opioid Peptide receptors:

  • action of morphine
  • Endorphins > Enk > Dyno
A

MU receptor

21
Q

= 61.5log[Ko+] / [Ki+] @ 37°C

A

Equilibrium Potential for K+
K+= -90mV
Cl= -70mV
Na = +60mV

22
Q

Amino acid sequence of CHON

A 
PRimary structure
(TN handout)
23
Q

Twists, folds, or twists and folds of AA seq into stabilized struc

A

SECONDARY structure

24
Q

Arrangement of twisted chains and folds w/n a protein into stable struxture.

A

Tertiary Structure

25
Q

Arrangement of subunits to form functional struc

A

Quarternary Structure

26
Q

Major Lipoprotein src of Cholesterol used in cells

A

LDL

27
Q

Bring about short term changes in cell fx by altering enzyme fx, trigger exocytosis, alteration of transcription.

A

Second messengers

28
Q

Organelles for postranslational process of proteins

A

GOLGI complex

29
Q

Plasma membrane proteins that couplr extracellular bindinh of primary signaling molecules yo activation of heterotrimeric G protein

A

G PROTEIN COUPLEE RECEPTORS

30
Q

Provides structural component for cell movement

A

FILAMRNTOUS ACTIN

31
Q

Nerve fiber with slowest conduction velocity

A

A alpha > A Beta > A delta > B > C

32
Q

Made of 3 polypeptide subunits
Express both p75NTR and TRK A receptors
Neccessary fo4 growth and devt of sympa and cholinergic neurons in basal forebrain and striatum

A

NERVE GROWTH FACTOR

33
Q

Latent Period

A

Conduction Velocity

34
Q

_____ is Essential for contraction, spread inwards to all parts of ms via the ____; Triggers release of ___

A
  • Action potential of skeletal ms
  • T tubules
  • Calcium
35
Q

Sliding in actin to produce shortening/crossbridging

A

Myosin

36
Q

Relaxing protein at rest by covering where myosin binds to actin

A

Tropomyosin

37
Q

More tension when ms contracts ____

More work when ms contracts ____

A

Isometrically

Isotonically

38
Q

Monoamines, catecholamines, amino acids

A

Small molecule transmitters

39
Q

Substance P
Enkephalins
Vasopressin

A

Large molecule transmitters

40
Q

Gaba b
VIP
NE
Metamorphic glutamate receptor

A

Metabotropic/GPCR

PLE Review CARDS by CHA (4 decks)

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