Pharmacology Flashcards

1
Q

Metformin - noteworthy side effect

A

Lactic acidosis

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2
Q

Antidote to beta-blockers

A

Glucagon

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3
Q

Antidote to copper, lead, arsenic and gold

A

Penicillamine

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4
Q

Iron chelator

A

Desferoxamine

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5
Q

Immediate reversal of haemorrhage in warfarin overdose

A

FFP

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6
Q

Trazadone - noteworthy side effect

A

Priapism (trazadone- trazabone)

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7
Q

Methanol- noteworthy side effects

A

Blindness

Anion-gap metabolic acidosis

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8
Q

ACEIs- noteworthy side effects

A
Cough
Rash
Proteinuria
Angioedema
Taste changes
Teratogenesis (renal agenesis)
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9
Q

Corticosteroid side effects

A
Depression and other psychopathology
Acute hyperglycaemia
Immunosuppression
Bone mineral loss
Osteonecrosis
Skin thinning
Easy bruising
Myopathy
Chronic cataracts
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10
Q

Penicillamine noteworthy side effect

A

Drug induced SLE

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11
Q

Phenytoin side effects

A

Nystagmus, diplopia, ataxia, arrhythmia (toxicity)
Gingival hyperplasia
Hirsuitism
Teratogenesis

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12
Q

Vancomycin side effects

A

Nephrotoxicity
Ototoxicity
Red man syndrome

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13
Q

Drugs that prolong QT interval

A

Antipsychotics

Fluoxetine + sertraline, TCAs

Methadone

Amiodarone

Azithromycin, clarithromycin, erythromycin

Ondansetron

Ketoconazole

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14
Q

Beta Blocker Contraindications

A

Systolic BP <90

Cardiogenic shock

Severe bradycardia

Second or third degree heart block

Asthma/ emphysema

Peripheral vascular disease

Uncompensated CHF

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