Mechanism Of Action

Question 0

Vancomycin

Answer 0

Bind to D-Ala-D-Ala terminus of nascent peptidoglycan

Question 1

Beta-lactams

Answer 1

Binds to penicillin-binding proteins

Inhibit transpeptidation in bacterial cell walls

Question 2

Aminoglycoside

Answer 2

Inhibit formation of initiation complex

Question 3

Tetracycline

Answer 3

Inhibit binding of tRNA to A site

Question 4

Chloramphenicol

Answer 4

Inhibit transpeptidation

Question 5

Clindamycin / Erythromycin

Answer 5

Inhibit translocation

Question 6

Sulfonamide

Answer 6

Inhibitor of folic acid synthesis

Competitive inhibitor of dihydropteroate synthase

Question 7

Trimethoprim

Answer 7

Selective inhibitor of bacterial dihydrofolate reductase

Question 8

Trimethoprim-Sulfamethoxazole

Answer 8

Sequential blockade of folate synthesis

Question 9

Fluoroquinolones

Answer 9

Inhibit topoisomerase II in gram neg

Topoisomerase IV in gram pos

Question 11

Rifampicin

Answer 11

Inhibits DNA dependent RNA polymerase

Question 12

Ethambutol

Answer 12

Inhibits arabinosyl transferases involved in synthesis of arabinogalactan

Question 13

Isoniazid

Answer 13

Inhibits mycolic acid synthesis