Calcium Chloride

Question 1

Pharm. and Action

Answer 1

Increases the force of myocardial contraction by initiation of of myofibril shortening; The positive inotropic effect and vasoconstricting effects produce a rise in systemic arterial pressure.

Question 2

Indications

Answer 2

In cardiac arrest setting= Hyperkalemia due to renal failure; Hypocalcemia due to multiple blood transfusions; Known or suspected calcium channel blocker overdose

Question 3

Contraindications

Answer 3

Cannot be administered with sodium bicarbonate; In presence of sodium bicarbonates, calcium salts will precipitate as carbonates

Question 4

Administration

Answer 4

Dose is 2-4 mg/kg IV. May be repeated if necessary.

Question 5

Side Effects and Special Notes

Answer 5

Extremely important to flush the IV line between administration of sodium bicarbonate and calcium chloride to avoid precipitation; May produce coronary or cerebral spasms; Should be used with caution in patients receiving digitalis; may precipitate toxicity

Question 6

Class

Answer 6

A