uworld wrong1

Question 1

what Valve problem and cause can be present after an MI and goes away after treatment

Answer 1

MR/due to papilary muscle dysfxn

Question 2

what heart sound preced S1

Answer 2

S4

Question 3

S4 heart sound is best heard in what position

Answer 3

putting the pt lying on there lft side(lft lat. decubitus)

Question 4

Verapamil MOA

Answer 4

Nondi-(heart) slows spontaneous depo( HTN, Afib, angina)

SE; prolactinoma, AV blk, bradycardia, constipation

Question 5

dystrophic calcification is a hallmark of what

Answer 5

cell injury/death(necrosis)

Question 6

what determines prognosis of TOF

Answer 6

Pulmonary stenosis(RV outflow obstruction)

Question 7

what are the mjr risk for AAA

Answer 7

> 65, SMOKING, Male

Question 8

what causes the continuous murmur in Coarctation of aorta

Answer 8

increased blood flow thru collateral blood vessels(internal thoracic art)

Question 9

Dialated cardiomyopathy is what type of hypertrohy

Answer 9

ECCENTRIC(increase vol)

Question 10

what are chlohexidine(causes leakage of cell membrane disruption) efective against

Answer 10

enveloped viruses, bacteria & fungi. NOT effective against nonenveloped icosahedral viruses(hep A picornavirus)

Question 11

what are sodium hypochlorite & chlorine DIOXIDE effective against

Answer 11

naked viruses, spores, protozoa, bacteria they DENATURE PROTEINS

Question 12

Histo of coagulative necrosis

Answer 12

Pale no nuclei also look for wedge shape in organ

Question 13

fibrinoid necrosis ouccurs in what

Answer 13

Vasculitis/malignant HTN

Question 14

what’s part of the intrinsic ptwy for apoptosis

Answer 14

mitochondria, cytochrome C, BCL2

Question 15

by what ptwy does negative selection induce apoptosis

Answer 15

FAS ligand (CD95) extrinsic

Question 16

melanosomes purpose

Answer 16

synthesis/storage of melanin

Question 17

what’s the mechanism behind partial albinism in chediak Higashi

Answer 17

due to abnormal intracellular transport of melanosomes cuz of mutation in the LYST

Question 18

Hyperchylomicronemia(I) risk of developing what?

Answer 18

def=Apo CII/LPL

pancreatitis, eruptive xanthoma, hepatosplenomegaly.

Question 19

what nerve can be effected in Prostectomy causing erectile DFX

Answer 19

cavernous nerve(originate from Inf. hypogastric plexus)

Question 20

In androgen Insensitivity Syndrome what are there presentation

Answer 20

Karyotipically male(46XY)
phenotypically=FEMALE blind vaginal pouch

Question 21

what would differentiate Insulinoma VS sulfonylureas

Answer 21

Insulin secretagogues is ABSENT in INSULINOMA but present in Sulfonylurea

Question 22

Cyclosporine causes what effect in the mouth

Answer 22

GINGIVAL HYPERPLASIA

Question 23

what drugs should be avoided in close angle glaucoma

Answer 23

Epi(a&B agonist) Atropine cause of mydriasis

Question 24

what are the liver flukes STEC

Answer 24

Schisto(mansoni Liver cancer, Hematobium Squamous bladder cancer)
TOXOCARA=from dog or cat diah & larva penetrate the owner skin
ECHINOCOCCUS=LIVER CYST
CLONORCHIS=INCREASE in ALP

Question 25

what is the fever cycle in P. malariae

Answer 25

every 3rd day

Question 26

what is the fever cycle in P. falci

Answer 26

every other day most fatal

Question 27

which Malariae lives in the RBC

Answer 27

viva, ovale, so when RBC dies it dies w/it

Question 28

How does Quinine, Mefloquine, Primaquine works

Answer 28

it oxidized RBC=Lyse it

Question 29

what anti Malaria drug is given for travel

Answer 29

Mefloquine (strt 2wks b4 travel, 1pill a wk b4 lvng & 4 wks after u return)

Question 30

what occurs in crossover study

Answer 30

every participant receives all the interventions but @ a diff time/sequence