Chlamydial Infection Flashcards

1
Q

What is chlamydia?

A
  • Caused by bacterium ‘Chlamydia trachomatis’
  • Bacteria found in semen of men + vaginal fluids of women
  • Easily passed on through UPSI
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2
Q

What are the symptoms of chlamydia in women?

A
  • Pain when urinating
  • Unusual vaginal discharge
  • Pain in the tummy/pelvis
  • Pain during sex
  • Bleeding after sex
  • Bleeding between periods
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3
Q

What are the symptoms of chlamydia in men?

A
  • Pain when urinating
  • White, cloudy or watery discharge from the tip of the penis
  • Burning or itching in the urethra (tube that carries urine out of the body)
  • Pain in the testicles
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4
Q

Why are chlamydia screening programmes important?

A

Offers free testing, treatment and partner management + prevention to sexually active young people under the age of 25.

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5
Q

What are the goals of the chlamydia screening programme?

A
  • Prevent + control chlamydia through early detection + treatment of asymptomatic infection
  • Reduce onward transmission to sexual partners
  • Prevent the consequences of untreated infection
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6
Q

What consequences can long-term infection of chlamydia cause?

A

Lead to serious long-term consequences.
Women = lead to Pelvic inflammatory disease, ectopic pregnancy + tubal infertility.
Men = can lead to epididymitis (inflammation of tube that carries and stores sperm) + epididymo-orchitis
Women + Men = lead to Reiter’s Syndrome (form of arthritis)

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7
Q

Why is chlamydia difficult to diagnose without the screening programme?

A

Many do not get symptoms, but easy to treat.

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8
Q

What are the 6 main aims of providing chlamydia testing in community pharmacies?

A
  1. Maximise capacity of CP + GP to deliver chlamydia testing, treatment + partner management = cost effective
  2. Increase access to the NCSP by providing additional locations to access testing
  3. Increase access to treatment of asymptomatic individuals
  4. Increase access for young people to sexual health advice
  5. Increase patients knowledge of the risks associated with STIs
  6. Strengthen the network of contraceptive + sexual health services to help provide easy + swift access to advice
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9
Q

What patients are suitable for chlamydia treatment in a pharmacy?

A
  • Provide chlamydia testing kits to people <25 e.g. if they are buying condoms, contraception or EHC
  • Advice on how to use the kit, how to return it for testing + what will happen following completion of the test

(Under 16 if Fraser competent can be provided)

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10
Q

What are the 5 Fraser guidelines?

A
  1. Young person (YP) understands HCP advice
  2. Cannot persuade YP to inform his/her parents that they’re seeking contraceptive advice
  3. YP is v likely to begin/continue having sex with or without contraceptive treatment
  4. Unless receives the treatment, the YP’s physical/mental health is likely to suffer
  5. YP’s best interests require the HCP to give contraceptive advice or treatment without parental consent
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11
Q

What do you do if a patient falls in the exclusion criteria of the PGD for the treatment with azithromycin for chlamydia?

A
  1. Explain reasons for exclusions with client + document
  2. Consider whether a doxycycline PGD could be used
  3. If not refer to GUM (sexual health clinic) or GP ASAP
  4. Male client with scrotal pain: consider immediate referral to A&E to exclude torsion of the testes
  5. Female client with pelvic pain: consider immediate referral to GUM or Gynaecology on-call service
  6. Presence of genital tract symptoms: consider immediate referral to GUM
  7. Concomitant conjunctivitis and/or joint pain: consider immediate referral to GUM/A&E
  8. Record in records
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12
Q

What is the medicine, dose and regimen for the treatment of chlamydia?

A

Azithromycin

  • 1 gram as a single dose
  • Taken as 4 x 250mg tablets
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13
Q

What verbal info should be given to patient before taking azithromycin?

A
  • Tablets should be swallowed whole with a cup of water
  • If food has been eaten within the last 2hours, delay administration.
  • Where possible avoid indigestion remedies.
  • If taking antacids, take azithromycin 1 hr before/2 hrs after.
  • Abstain completely from sexual contact for 7 days after your treatment and partners treatment.
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14
Q

What advice should be given is a patient is treated for chlamydia and is using oral contraception?

A
  • Take as usual
  • If given antibiotics in 1st week of pill packet + had sex recently = may require EHC
  • If client is at end of packet for the combined pill whilst taking or within 7 days after taking, advise to start new packet straight away.
  • Do NOT have the usual 7 day break or take placebo tablets.
  • Bleeding is normal
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15
Q

What are the side effects of azithromycin?

A
  • Anorexia
  • Dyspepsia (indigestion)
  • Constipation
  • Dizziness
  • Headache
  • Drowsiness
  • Risk of thrush
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16
Q

What drugs interact with azithromycin?

A
  • WARFARIN - effects may be increased by macrolides
  • STATINS - cases of rhabdomyolysis (rapid breakdown of skeletal muscle cells)
  • CICLOSPORIN - azithromycin affects clearance
  • DRUGS PROLONGING QT INTERVAL - all maceolides prolong further
  • DRUGS THAT CAUSE HYPOKALAEMIA (low K+) - risk factor for QT prolongation