Application of stem cells Flashcards

1
Q

What is the most well-established and widely used stem cell treatment?

A

The transplantation of blood stem cells to treat diseases.

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2
Q

How many patients are treated with blood stem cells in Europe each year?

A

More than 26,000 patients

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3
Q

What stem cells been used for patients with severe burns on very large areas of the body?

A

Since the 1970s, skin stem cells have been used to grow skin grafts for patients with severe burns on very large areas of the body.

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4
Q

TRUE or FALSE:

Currently, these are very few stem cell therapies that have been thoroughly established as safe and effective treatments.

A

TRUE

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5
Q

What was the first stem cell-based medicinal product approved in the Western world?

A

Holoclar®

Uses a particular type of eye stem cell, called a limbal stem cell, to repair the cornea after injury; restoring sight.

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6
Q

Blood stem cells: the pioneers of stem cell research

A
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7
Q

What are the main sources of stem cells?

A
  • Bone Marrow
  • Blood stream
  • Umbilical cord
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8
Q

Future applications of stem cells

A
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9
Q

Patient derived
Induced pluripotent stem cells

A
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10
Q

What are the potential uses of stem cells?

A
  • Improve our understanding of how the body develops from a fertilized egg; this can also provide insights into how our adult tissues are maintained and repaired in health
  • Understand how diseases occur and develop; a number of diseases, such as cancer or birth defects, are the result of problems in the process of differentiation from stem cells to more specialized cells
  • Search for and test potential new drugs by studying cells in the laboratory
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11
Q

Drug development

A
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12
Q

Drug screening/development

A
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13
Q

The embryonic stem cell test

A

•Only validated in vitro assay for potential embryotoxicants

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