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Pharmakologie > Questions > Flashcards

Questions Flashcards

1
Q

Venlafaxin fuehrt zu…

A

Absetzsymptome

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2
Q

Milnacipran

A

keine CYP-Metabolisierung

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3
Q

Wieso kann es vorteilhaft sein wenn ein Wirkstoff keine CYP-Metabolisierung beauftraegt?

A

Vorteil bei Kombination von Pharmaka

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4
Q

Welches Antidepressivum fuehrt zu die staerkste Gewichtszunahme?

A

Olanzapin

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5
Q

Valproinsaeure hat eine _______________ Wirkung

A

antiepileptische

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6
Q

Tranylcypromin

A

Abbau von Tyramin

irreversible

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7
Q

Bupropion

A

NDRI

–> KEINE SEXUELLE FUNKTIONSSTOERUNG

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8
Q

Was fuer Arzneimittel werden intravenoes eingenommen?

A

Narkotika

Propofol

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9
Q

Was fuer Arzneimittel werden intramuskulaer eingenommen?

A

Neuroleptika

Depotmedikamente

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10
Q

CYP-Enzyme sind nicht ___________.

A

identisch

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11
Q

Hemmung von CYP fuehrt zu …

A

Erhoehung der Plasmakonzentration vom Arzneimittel

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12
Q

Nennen Sie die 4 Formen der Biotransformation

A

Influx
Funktionalisierung
Konjunktion
Efflux

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13
Q

Wo findet Biotransformation statt?

A

in der Leber

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14
Q

Effekt von Kokain im Herz?

A
  • hemmt NA-Aufnahme
    in die sympathische Neurone

(NAT-Inhibitor)

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15
Q

Das meist verordnete Antidepressivum?

A

Amitriptylin

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16
Q

Phase 1 der Biotransformation?

A

Hydroxylation

CYP

17
Q

Phase 2 der Biotransformation

A

Glucoronidierung

18
Q

Funktion der Glucoronidierung?

A

wasserlöslich machen

für die Ausscheidung

Pharmakologie (6 decks)

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