pancreas Flashcards

1
Q

how do gallstones affect the pancreas

A

cause pancreatitis if blocking the common bile duct

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2
Q

what are the 2 main issues when the pancreas is damaged

A

digesting food and maintaining blood glucose

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3
Q

what are the main symptoms of pancreatic issues

A
diarrhoea
bloating
flatulence
oily and foul smelling, fatty stools
weight loss
malnutrition
poor blood sugar control
diabetes
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4
Q

what are the risk factors for pancreatic pathology

A

alcohol consumption
high fat diet and obesity
tobacco products
genetics - CF

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5
Q

what is acute pancreatitis

A

sudden inflammation of the pancreas, intense pain and requires hospital

enzymes are activated before they leave the pancreas and start to attack pancreatic tissue

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6
Q

what are the causes of AP

A

heavy alcohol use
gallstones
idiopathic
abdominal trauma, medication like HT, diuretics etc, tumours, infections

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7
Q

what are the signs of AP

A

intense pain in centre upper abdomen
radiates to back
nausea and vomiting
fever?

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8
Q

what are the investigations for AP

A

blood tests - amylase and lipase levels elevated

CT scan confirms it

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9
Q

what treatment is for AP

A
IV fluids
analgesia
help feeding
severe: cholectomy if cause is gallstones
after: lifestyle changes
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10
Q

what is chronic pancreatitis

A

long-term inflammation of the pancreas - irreversible destruction of pancreatic tissue

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11
Q

what are the causes of chronic pancreatitis

A

long term alcohol or smoking
medications
elevated triglycerides, CF, hereditary, auto-immune

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12
Q

what are the consequences of CP

A

lack of correct digestion so patients have difficulty absorbing nutrients from food = gaining weight difficulties, weak bones, vision loss

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13
Q

what are the chronic symptoms of CP

A

intermittent abdominal stabbing pain, in RUQ, may be triggered by eating
can be constant

weight loss, oily stools, diabetes

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14
Q

what are the investigations for CP

A

abdo CT, endoscopic USS, pancreatic stimulation testing where pancreatic liquid is collected from the intestine and analysed every 2 hours

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15
Q

what is the treatment for CP

A

lifestyle changes
pain management
medication: pancreatic enzyme replacement therapy: lipase, creon
multi-vits

surgery for unremitting pain

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16
Q

what are the endocrine and exocrine cells of the pancreas and what are the differences

A

exocrine - acinar - enzymes into ducts first

endocrine - islets of langerhans - hormones into blood straight away

17
Q

what do delta cells secrete

A

somatostatin

18
Q

what else do beta cells secrete

A

AMYLIN