Ageing Process Flashcards
1
Q
list cellular factors contributing to ageing
A
mutations in chromosomes and mitochondria
intracellular and extracellular aggregates
cellular loss
cellular senescence
extracellular protein cross links
2
Q
what are telomeres and what happens to them during ageing
A
tips of chromosome, shorten throughout life due to cell division
leading to cell senescence
3
Q
describe frailty
A
increased vulnerability to decompensation after a stressor event
loss of homeostasis and resilience
4
Q
describe multimorbidity
A
having more than one chronic health condition increases risk of adverse events, poorer quality of life and hospital admission
