Germ Cell Flashcards
Why can men develop gynae Onassis when they have a testicular cancer?
If BHCG is raised
What investigations should be performed for a testicular mass?
Bilateral testicular USS
BHCG
AFP
LDH
CT TAP
MR brain (if choriocarcinoma or poor prognostic group)
Sperm banking (HIV, Hep b&c, syphilis screen)
Biopsy usually from the radical inguinal orchidectomy
What distinguishes T1 and T2?
Both limited to testis and epididymis but T2 if has vascular/lymphatic invasion or involvement of tunica vaginalis
Describe N1
<=5LN all <=2cm
Describe N2
2-5cm
Or
>5LNn all <5cm
Describe N3
> 5cm
What TNM is stage 1?
AnyT N0 S1-3
What is classed as a high risk stage 1 seminoma?
Size >4cm or rete testis involvement
If neither of these risk of recurrence ~10%
If one of these risk is ~15%
If both, 30%
What is the preferred treatment option for stage 1 seminoma with high risk features?
Carboplatin AUC7 x 1
Or
20Gy/10# para-aortic XRT
Define the field borders for para-aortic XRT
Sup: bottom of T10
Inf: bottom of L5
Lateral: border to edge of renal hilum
Define stage IIA
Tany N1 M0 S0-1