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Simmons NURP 503 Exam 3 > 9: Treatment Options > Flashcards

9: Treatment Options Flashcards

1
Q

T/F Some chemotherapy drugs are considered chemo only when used in combination with other drugs.

A

True. For example, dexamethasone is chemo when combined with velcade and cytoxan for multiple myeloma.

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2
Q

Which stage of the cell cycle: G0, G1, S, G2, or M?

Mitosis (cell splits into 2).

A

M

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3
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Adriamycin, Bleomycin.

A

Antitumor antibiotics

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4
Q

Photon or particle ionizing radiation?

Protons

A

Particle (ionizing) radiation

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5
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Stop mitosis or inhibit enzymes from making proteins required for cell reproduction.

A

Mitotic inhibitors

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6
Q

T/F Watchful waiting can make some patients uncomfortable, but some cancers may not require therapy for years.

A

True. Chronic lymphocytic leukemia you monitor in the WBC. May not require treatment for years.

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7
Q

Which stage of the cell cycle: G0, G1, S, G2, or M?

Apparatus for mitosis is built.

A

G2

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8
Q

Which stage of the cell cycle: G0, G1, S, G2, or M?

RNA and protein synthesis are made for dividing.

A

G1

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9
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Interfere with enzymes called topoisomerases (help separate strands of DNA for replication).

A

Topoisomerase inhibitors

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10
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Taxol, Taxotere, Vincristine

A

Mitotic inhibitors

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11
Q

T/F Radiation effects can linger for decades.

A

True. Uncommon, but can increase secondary malignancies or cause idiopathic pulmonary fibrosis, for example.

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12
Q

Photon or particle ionizing radiation?

Electrons

A

Particle (ionizing) radiation

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13
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Irontecan, Etoposide

A

Topoisomerase inhibitors

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14
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Cytoxan, Cisplatin, platinum-based therapies.

A

Alkylating agents

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15
Q

Photon or particle ionizing radiation?

Neutrons

A

Particle (ionizing) radiation

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16
Q

_____ is hormone therapy used to treat prostate cancer.

A

Lupron

17
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
5-FU, Pemetrexed

A

Antimetabolites

18
Q

Which stage of the cell cycle: G0, G1, S, G2, or M?

DNA synthesis.

A

S

19
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Interfere with DNA and RNA growth, specifically during S phase.

A

Antimetabolites

20
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Commonly used to treat ovarian cancer.

A

Alkylating agents

21
Q

Photon or particle ionizing radiation?

Gamma rays

A

Photon (ionizing) radiation

22
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Can cause neuropathy.

A

Alkylating agents

23
Q

Cancer management (4).

A
  1. Watchful waiting
  2. Chemo
  3. Radiation
  4. Surgery
24
Q

Photon or particle ionizing radiation?

Most widely used in cancer treatment.

A

Photon (ionizing) radiation

25
Q

Photon or particle ionizing radiation?

X-rays

A

Photon (ionizing) radiation

26
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Directly damage DNA and prevent cancer cells from reproducing and growing.

A

Alkylating agents

27
Q

T/F Debulking surgery is common for most solid tumors.

A

True. It can help relieve symptoms.

28
Q

Which stage of the cell cycle: G0, G1, S, G2, or M?

Cell rests from dividing and does its normal physiologic work.

A

G0

29
Q

Tarceva targets the _____ mutation in lung cancer patients.

A

EGFR

30
Q

During which cell cycle is radiation least effective?

A

G0 (slowly dividing)

31
Q

Alkylating agents, antimetabolites, antitumor antibiotics, topoisomerase inhibitors, or mitotic inhibitors?
Interfere with enzymes involved in DNA replication.

A

Antitumor antibiotics

Simmons NURP 503 Exam 3 (18 decks)

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