Microbiology

Question 1

HBV belongs to which virus family of the following?

1. Hepeviridae.
2. Hepadnaviridae.
3. Picornavirifae.
4. Flavivirdae.
5. Non of the above

Answer 1

3. Hepadnaviridae.

Question 2

HAV belongs to which virus family of the following?

1. Hepeviridae.
2. Hepadnaviridae.
3. Picornavirifae.
4. Flavivirdae.
5. Non of the above

Answer 2

3. Picornaviridae.

Question 3

HEV belongs to which virus family of the following?

1. Hepeviridae.
2. Hepadnaviridae.
3. Picornavirifae.
4. Flavivirdae.
5. Non of the above

Answer 3

1. Hepeviridae.

Question 4

HCV belongs to which virus family of the following?

1. Hepeviridae.
2. Hepadnaviridae.
3. Picornavirifae.
4. Flavivirdae.
5. Non of the above

Answer 4

4. Flaviviridae.

Question 5

HDV belongs to which virus family of the following?

1. Hepeviridae.
2. Hepadnaviridae.
3. Picornavirifae.
4. Flavivirdae.
5. Non of the above

Answer 5

5. Non of the above

Question 6

Enumerate the enveloped and non enveloped hepatitis viruses.

Answer 6

Enveloped : B, C, D.

Non-Enveloped : A, E.

Question 7

Classify hepatitis viruses according to their capsid structure.

Answer 7

A, E, B&raquo_space;> Icosahedral capsid.

C, D&raquo_space;> Spherical capsid.

Question 8

The genome of HBV is ……

1. • sense SS RNA
2. +sense SS RNA
3. ds DNA
4. ALL OF THE ABOVE
5. NONE OF THE ABOVE

Answer 8

3. ds DNA

Partially.

Question 9

What are possible MOTs for HBV

Answer 9

Parental route
Perinatal route
During sexual intercourse

Question 10

What are possible MOTs for HCV?

Answer 10

Parental route
Perinatal route
Organ transplantation

Question 11

What is the treatment of HBV?

Answer 11

Alpha interferon

Lamivudine (nucleoside analogue)

Question 12

What is the treatment of HCV?

Answer 12

1. Alpha interferon + Ribavirin + sovaldi
2. Harvoni (sovaldi + Ledipasvir)&raquo_space;Inhibit NS5A synthesis
   «» Inhibit RNA Polymerase

Question 13

Monitoring of HCV treatment

Answer 13

Quantitative PCR to count viral load
After 4 ws of therapy beggening
At the end of therapy
After 12 ws of therapy

Question 14

HAV Post exposure prophylaxis for close contacts.

Answer 14

@1 - 40 years&raquo_space;> hepatitis vaccine only
@Above 40 years&raquo_space;> hepatitis A vaccine + Immunoglobulin
@Less than month&raquo_space;> Immunoglobulin only
##Vaccine&raquo_space;> inactivated