[march]Alzheimer’s Disease

Question 1

What?

Answer 1

• disorder which causes brain cells to degenerate and die.

- incurable disease, as the death of brain cells cannot be reversed

Question 2

Impacts?

Answer 2

loss of memory,
problems with words in speaking or writing, poor judgment,
changes in mood and personality, confusion with time or place

Question 3

What is dementia?

Answer 3

• group of brain disorders that cause the loss of intellectual and social skills.
• Alzheimer’s is the most common cause of dementia

Question 4

Why?

Answer 4

build-up of proteins known as tau tangles or plaques

Question 5

What is Tau?

Answer 5

Tau is a protein that when it occurs in tangled formations in the brain of Alzheimer patients, disrupts the ability of neurons to communicate with one another in the brain.

Question 6

Context?

Answer 6

Researchers from Jawaharlal
Nehru Centre for Advanced
Scientific Research
( JNCASR), Bengaluru, have
developed a small molecule
that helps disrupt and reduce
formation of amyloid
plaques in the brains of mice
with Alzheimer’s Disease.

Name of molecule : TGR63.