PO DM meds MOA

Question 1

metformin works at the _______

Answer 1

liver

Question 2

metformin works at the ______ to decrease ________ and decrease __________

Answer 2

• liver
• gluconeogenesis
• insulin resistance (aka, increase sensitivity)

Question 3

TZD works at the _______

Answer 3

nucleus

Question 4

TZD works at the ______ to increase _________

Answer 4

nucleus
insulin sensitivity (aka decrease resistance)

Question 5

AGI’s work at the ______

Answer 5

intestine

Question 6

AGI’s work at the _______ to decrease ________ absorption and delay __________

Answer 6

intestine
glucose
gastric emptying

Question 7

GLP1 work at the _______

Answer 7

pancreas

Question 8

GLP1 work at the __________ to increase __________

Answer 8

pancreas

insulin secretion

Question 9

DPP4 works at the _______

Answer 9

pancreas

Question 10

DPP4 works at the _________ to increase _________

Answer 10

pancreas

insulin secretion

Question 11

SUs work at the ______

Answer 11

pancreas

Question 12

SUs work at the _______ to increase _______

Answer 12

pancreas

insulin secretion

Question 13

SGLT2 works at the _______

Answer 13

proximal renal tubule

Question 14

SGLT2 works at the _________ to increase renal ________

Answer 14

proximal renal tubule

glucose excretion