Investigations Flashcards
How would you investigate dysphagia?
- Bloods: haematinics, FBC, U+E’s, LFTs
- CXR
- OGD
- Barium swallow
What are the investigations for pancreatitis?
Amylase (lipase more sensitive) - levels 3x normal amylase
Examination - Cullen’s sign around umbilicus
What are the investigations for gallstones?
- LFTs - obstructive
Raise in ALP first, then bilirubin.
Bilirubin rise when CBD stone. - WCC + CRP - cholecystitis, cholangitis
- USS - confirmation of gallstones
- MRCP - to identify CBD stone (obstructive LFTs)
- ERCP - camera to remove stones and stent
What are the investigations for pancreatic cancer?
- Courvoisier’s law - palpate gallbladder
- Markers: Ca19-9
- Imaging CT, CT/PET if still unclear/looking for mets
- ERCP to remove biliary obstruction
What are the investigations for asthma?
- PEFR
- Spirometry + BDR (bronchodilator reversibility)
- FeNO
- Sputum culture
What are the investigations for COPD?
- ECG
- Spirometry
- Sputum culture
- AATD
What are investigations for HF?
- Cardio exam
- NTproBNP/BNP
- Lipid profile
- Echo
What are the investigations for pneumonia?
- Blood cultures
- Sputum culture
- Urine antigen
- CRP/FBC
- CURB-65
- ABG
- ECG
What are the investigations for PE?
- D-dimer
- CTPA
- US
- V/Q scan
- Wells score (if <4 do d-dimer)
What investigations for a pneumothorax?
- ABG
- CXR
What are the exudative results for pleural effusion?
- Causes: pancreatitis, infection, neoplasia, PE
- Pleural protein >35g/L
- Pleural fluid : serum protein - >0.5
- Pleural fluid : serum LDH - >0.6
- Pleural fluid LDH more than 2/3 upper limits of normal serum LDH
What are obstructive spirometry results?
FEV1 very low
FVC normal/low
Ratio <70%
Causes: COPD, asthma, bronchiectasis, CF
What are restrictive spirometry results?
Low FEV1/FVC
Ratio >70%
Causes: pulmonary fibrosis, sarcoidosis, lobectomy, scoliosis
What are investigations for lung cancer?
- 2WW
- Bloods - rule out infective causes, potentially hyponatremia (SIADH - SCLC)
- CXR
- EBUS
- CT TAP
- PET-CT
What are investigations for bowel cancer?
- Faecal occult blood
- Sigmoidoscopy/colonoscopy
- Biopsy
- Staging CT CAP