breast stuff missed Flashcards

1
Q

triple assessment include

A

clinical
imaging - mammogram + US
pathology - US guided core biopsy

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2
Q

what is the secretory cell in breast

A

acini

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3
Q

what cells in the breast contract to eject milk

A

myoepithelial

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4
Q

benign breast tumours

A

phyllodes tumour

intraductal papilloma

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5
Q

non neopastic breast diseases

A
gynaecomastia
fibrcystic change 
hamartoma
fibroadenoma
scelrosing lesion
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6
Q

what drugs can cause fat necrosis of breast

A

warfarin

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7
Q

leaf tumour

A

phyllodes

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8
Q

what type of carcinomas are breast carcinomas

A

adenocarcinomas

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9
Q

types of breast carcinoma

A

ductal and lobular

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10
Q

precursor lesions to lobular neoplasia

A

atypical lobular hyperplasia

lobular carcinoma in situ

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11
Q

features of lobular neoplasia

A

multifocal and bilateral
not palpable - incidental finding
may calcify - seen on mammogram

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12
Q

what is pagets disease of the nipple

A

high grade DCIS oxtending down duct to nipple . still an in situ carcnoma

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13
Q

management of DCIS

A

surgery
adjuvant XRT
chemoprevention

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14
Q

what identifies an invasive breast carcinoma

A

has broken through basement membrane with poss metastesis

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15
Q

give examples of anti oestrogen therapy

A

oophrectomy
tamoxifen ( OE receptor antag )
aromatase inhibitors -letrozole
GnRH analogues - goserelin

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16
Q

what gives the bests prognosis in terms on receptor expression in breast cancer

A

OE +
PR +
HER2 -

17
Q

what is the proper name of herceptin

A

trastuzamab - monoclonal antibody

18
Q

what cancer is US low sensitivity for

A

DCIS

19
Q

what is the most sensitive imaging modality for breast Ca

A

MRI