A. 2) Translation: Rough ER Flashcards
1
Q
what is required for initiation of translation
A
mRNA CAP and euakaroytic initiation factors like eIF4G. If the protein has an N terminal signal seuence, the ribosome bound to the mRNA is directed to the ER
2
Q
when will the protein be inserted into the ER membrane
A
if the final location of the protein will be an integral membrane protein
3
Q
when will the protein be released inside the ER
A
proteins that will either be secreted by cell or stored in lysosomes
4
Q
what happens to the signal sequence
A
it is removed from all the proteins during translation
5
Q
what else will form (bond)
A
if protein has disulphide bonds
