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BACTE LEC PRELIMS > AAAST 1 > Flashcards

AAAST 1 Flashcards

(31 cards)

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1
Q

Used together with penicillins often

A

Aminoglycosides

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3
Q

Calcium chelated

A

Tetracycline

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4
Q

Antimicrobial susceptibility has been lost

A

Clinical resistance

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5
Q

Short dna sequences - transposable element

A

Insertion sequences

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6
Q

Inhibit protein synthesis (2)

A

Tetracycline and dexocycline

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8
Q

Reduced susceptibility of an organism to a microbial agent

A

Biological resistance

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9
Q

Formation of persister cells

A

Biofilms

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11
Q

Inherent resistance of Gr (-) bacteria to Vancomycin

A

Impermeability; intrinsic resistance

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12
Q

INTRINSIC OR ACQUIRED RESISTANCE

Decreased penetration of antibiotic

A

Intrinsic

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13
Q

Production of enzymes that destroy antimicrobial agents

A

Enzyme inactivation

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14
Q

INTRINSIC OR ACQUIRED RESISTANCE

Embedded in exopolysaccharide matrix

A

Intrinsic

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15
Q

Acquired resistance happen due to

A

Abuse of antibiotic

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16
Q

MRSA means

A

Methicillin Resistant Staphylococcus aureus

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17
Q

INTRINSIC OR ACQUIRED RESISTANCE

Resistance to beta lactam drugs

A

Acquired

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18
Q

ESBL

A

Extended Spectrum Beta Lactamase

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19
Q

What r the ESBLs

20
Q

Drug of choice for MRSA

21
Q

Jumping genes

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A

Transposons (?)

22
Q

INTRINSIC OR ACQUIRED RESISTANCE

Glycopeptide resistance

23
Q

For mycoplasma, treponemes, rickettsia

24
Q

INTRINSIC OR ACQUIRED RESISTANCE

Biofilms

25
Q

Enzymatic alterations involving a plasmid borne variant of an enzyme

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A

Resistance to quinolones

26
Q

Inhibit protein synthesis by interacting with 23s rRNA

28
Q

Most important strategy of bacteria to spread resistance

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A

Lateral gene transfer

29
Resistance to folate pathway inhibitors mean
Target site substitution
31
Causes pseudomembranous colitis
Clindamycin
32
Linezolid is a
Oxazolidinones
33
Used before for typhoid
Chloramphenicol
34
Limited spectrum of action
Narrow spectrum
35
Mobile genetic elements
Integrins
38
Meaning of resistance to macrolides
Altered cell wall precursors unable to bind to vancomycin

BACTE LEC PRELIMS (2 decks)

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