AB Flashcards

1
Q

streptomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S fout AZ

2 - // - 5 - //

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2
Q

dihydrostreptomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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3
Q

neomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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4
Q

gentamicine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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5
Q

amikacine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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6
Q

tobramycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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7
Q

kanamycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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8
Q

paromomycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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9
Q

apramycine

A

aminoglycosiden (streptomycine, dihydrostreptomycine, neomycine, gentamicine, amikacine, tobramycine, kanamycine, paromomycine, apramycine) -> 30S

2 - // - 5 - //

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10
Q

spectinomycine

A

aminocyclitols (enige: spectinomycine) -> 30S

2 - // - 5 - //

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11
Q

colistine

A

polymyxines (verdringen tweewaardige ionen thv fosfolipiden)

// - // - 5 - 2
gram+ zijn resistent

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12
Q

chloramfenicol

A

fenicolen (chloramfenicol, thiamfenicol, florfenicol) -> 50S

5 - 5 - 3 - 5

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13
Q

thiamfenicol

A

fenicolen (chlorfenicol, thiamfenicol, florfenicol) -> 50S

5 - 5 - 3 - 5

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14
Q

florfenicol

A

fenicolen (chlorfenicol, thiamfenicol, florfenicol) -> 50S

5 - 5 - 3 - 5

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15
Q

tetracycline

A

tetracyclines 1 (tetracycline, oxytetracycline, chlortetracycline) -> 30S

2 - 2 - 2 - 2

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16
Q

oxytetracycline

A

tetracyclines 1 (tetracycline, oxytetracycline, chlortetracycline) -> 30S

2 - 2 - 2 - 2

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17
Q

chlortetracycline

A

tetracyclines 1 (tetracycline, oxytetracycline, chlortetracyline) -> 30S

2 - 2 - 2 - 2

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18
Q

doxycycline

A

tetracyclines 2 (enkel doxycycline) -> 30S

4-4-4-4

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19
Q

sulfasalazine

A

sulfonamiden -> competitie PABA voor dehydropteroaat synthetase enzym -> inhibitie foliumzuur

2 - 2 - 2 - 2

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20
Q

sulfadiazine

A

sulfonamiden (competitie met PABA voor dihydropteroaat synthetase enzym -> inhibitie foliumzuur)

2- 2 - 2 -2

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21
Q

sulfachlorpyrazine

A

sulfonamiden (competitie met PABA voor dihydropteroaat synthetase enzym -> inhibitie foliumzuur)

2 - 2 - 2 - 2

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22
Q

sulfamethoxazole

A

sulfonamiden (competitie met PABA voor dihydropteroaat synthetase enzym -> inhibitie foliumzuur)

2 - 2 - 2 - 2

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23
Q

trimethoprim

A

diaminopyrimidines (inhibitie dihydrofolaat reductase enzyme -> geen DNA synthese)

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24
Q

nitrofurantoine

A

nitrofuranen -> remming Krebs enzymen

25
nalidixinezuur
fluoroquinolonen 1 (nalidixinezuur, flumequine) -> inhibitie DNA gyrase en topoisomerase IV // - // - 3 - //
26
flumequine
fluoroquinolonen 1 (nalidixinezuur, flumequine) -> inhibitie DNA gyrase en topoisomerase IV // - // - 3 - //
27
marbofloxacine
fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV 2 - // - 5 - //
28
danofloxacine
fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV 2 - // - 5 - //
29
danofloxacine
fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV 2 - // - 5 - //
30
enrofloxacine
fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV 2 - // - 5 - //
31
orbifloxacine
fluoroquinolonen 2 (marbofloxacine, danofloxacine, enrofloxacine, orbifloxacine) -> inhibitie DNA gyrase en DNA topoisomerase IV 2 - // - 5 - //
32
pradofloxacine
fluoroquinolonen 3 (enkel pradofloxacine) -> inhibitie DNA gyrase + DNA topoisomerase IV 5 - 2 - 5 - 2
33
cloxacilline
penicillines (resistent) -> inhibitie transpeptidatie -> disruptie celmembraan staph/strep - // - // - //
34
ampicilline
penicillines (breed spectrum: ampicilline, pivampicilline, amoxicilline) -> inhibitie transpeptidatie -> disruptie celmembraan 4 - 4 - 4 - 4
35
pivampicilline
penicillines (breed spectrum: ampicilline, pivampicilline, amoxicilline) -> inhibitie transpeptidatie -> disruptie celmembraan 4 - 4 - 4 - 4
36
amoxicilline
penicillines (breed spectrum: ampicilline, pivampicilline, amoxicilline) -> inhibitie transpeptidatie -> disruptie celmembraan 4 - 4 - 4 - 4
37
cefazoline
cephalosporines 1 (cefazoline, cefapirin, cefalexine) -> inhibitie transpeptidatie -> disruptie membraan 5 - 5 - 2 - 5
38
cefapirin
cephalosporines 1 (cefazoline, cefapirin, cefalexine) -> inhibitie transpeptidatie -> disruptie membraan 5- 5 - 2 - 5
39
cefalexine
cephalosporines 1 (cefazoline, cefapirin, cefalexine) -> inhibitie transpeptidatie -> disruptie membraan 5 - 5 - 2 - 5
40
ceftiofur
cephalosporines 3 (ceftiofur, cefovecin, cefoperazone) -> inhibitie transpeptidatie -> disruptie membraan 4 - 4 - 4 - 4
41
cefovecin
cephalosporines 3 (ceftiofur, cefovecin, cefoperazone) -> inhibitie transpeptidatie -> disruptie membraan 4 - 4 - 4 - 4
42
cefoperazone
cephalosporines 3 (ceftiofur, cefovecin, cefoperazone) -> inhibitie transpeptidatie -> disruptie membraan 4 - 4 - 4 - 4
43
cefquinome
cephalosporines 4 (enige: cefquinome) -> inhibitie transpeptidatie -> disruptie membraan 4 - 4 - 4 - 4
44
clavulaanzuur
beta-lactamase inhibitor -> geen antimicrobiële activiteit
45
erythromycine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S 5 -5 - 2 - 5
46
spiramycine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S 5 - 5 - 2 - 5
47
tylosine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S 5 - 5 - 2 - 5
48
acetylisovaleryltylosine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S mycoplasma, R. equi, diarree bij oraal 5 - 5 - 2 - 5
49
tilmicosine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S 5 - 5 - 2 - 5
50
tulathromycine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S 5 - 5 - 2 - 5
51
azithromycine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S
52
clarithromycine
macroliden (erythromycine, spiramycine, tylosine, acetylvaleryltylosine, tilmicosine, tulathromycine, azithromycine, clarithromycine) -> 50S 5 - 5 - 2 - 5
53
lincomycine
lincosamiden (clindamycine, lincomycine, pirlimycine) -> 50S 5 - 3 - 2 - 3
54
clindamycine
lincosamiden (clindamycine, lincomycine, pirlimycine) -> 50S 5 - 3 - 2 - 3
55
pirlimycine
lincosamiden (clindamycine, lincomycine, pirlimycine) -> 50S 5 - 3 - 2 - 3
56
tiamuline
pleuromutilins (samen met valnemuline) -> 50S inhibeert CYP: hoge gehalte ionofore coccidiostatica! 4 - 4 - 2 - 4
57
valnemuline
pleuromutilins (samen met tiamuline) -> 50S 4 - 4 - 2 - 4
58
rifampicine
rifamycines -> inhibitie RNA polymerase nodig voor omzetting DNA naar RNA R. equi, diarree paard