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Prudent use > Ab in Swine > Flashcards

Ab in Swine Flashcards

1
Q

How can Enrofloxacin be given to swine?

A

IM & PO

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2
Q

How is Marbofloxacin given in swine?

A

IM

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3
Q

how is ceftiofur given in swine

A

im

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4
Q

how is Cefquinome given in Swine?

A

im

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5
Q

How can colistin be given in Swine?

A

im or po

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6
Q

Enrofloxacin, Marbofloxacin, Ceftiofur, Cefquinome are category?

A

B

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7
Q

how can amox+clav be given in swine

A

po & im

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8
Q

1st choice in swine E.Coli Enteritis?

A

Gentamycin

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9
Q

Gentamycin has a … absorption in gut (swine)

A

poor absorption (5%) –> high C in gut

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10
Q

Which one is broad spectrum & bacteriostatic, but bactericidal in the resp tract

  • gentamycin
  • amox+clav
  • florfenicol
  • lincomycin
A

florphenicol

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11
Q

flophenicol can be given (swine):

  • po
  • im
  • both
  • none
A

both

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12
Q

lincomycin can be given (swine)

A

po & parenteral

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13
Q

spectinomycin & lincomycin should given

  • orally
  • parenterally
A

parenterally - poor oral absorption of spectinomycin

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14
Q

which ones is bacteriostatic, but bactericidal in the lung?

  • Tiamulin
  • valnemulin
  • tylvalosin
  • Tilmicosin
  • Macrolides
A

Tiamulin & valnemulin & Macrolides

reaches high concentration in the lung

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15
Q

Which are the 2 forms of Tylosin ?

A

Tylosin - tartarate

Tylosin - phosphate

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16
Q

Which Tylosin should be used in resp tract infection?

  • Tylosin - tartarate
  • Tylosin - phosphate
A

Tylosin tartarate

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17
Q

Which Tylosin should be used in GIT infection (proliferative enteritis)?

  • Tylosin - tartarate
  • Tylosin - phosphate
A

Tylosin Phosphate

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18
Q

Which one has the worst absorption?

  • Tylosin - tartarate
  • Tylosin - phosphate
A

Tylosin phosphate

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19
Q

Tylvalosin should be given

  • po
  • im
  • sc
A

po

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20
Q

Tylvalosin is active against

  • mycoplasma
  • lawsonia intracellularis
  • brachyspira hyodysenteriae
  • all
A

all

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21
Q

What is an side effect if tilmicosin is used parenterally ?

A

cardiotoxic effect

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22
Q

tilmicosin should be given…

A

… PO

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23
Q

Tulathromycin should be given

  • iv
  • im only
  • iv and im
  • sc
A

im only

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24
Q

tulathromycin is effective against

A

mycoplasma + gram neg fastidious

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25
tildipirosin should be given
im
26
Can Penicillin be given Po in Swine?
no, it is off label
27
Amox and PotSA can be given :
PO and parenteral
28
Which lesion is caused by Cl.perfringens C in Swine? - ulcerative enteritis - necrotic enteritis
necrotic enteritis
29
Why can Penicillins be used in Cl.perfringens C infections in swine?
Cl.perfringens C doesn't produce beta lactamase
30
Which penicillin cannot be used in Cl.perfringens C infections in swine?
Phenoxymethyl penicillin - off label
31
Which penicillin should be given PO in Cl.perfringens C infections?
Amoxicillin
32
In what age can swine get sick of Cl.perfringens C ?
It is a disease of suckling pigs
33
Escherichia Coli in swine - age class
suckling piglets and weaned pigs
34
E.Coli Strains are usually resistant to which catergory ?
AB of category D
35
Which are the big guns against E.Coli?
Ceftiofur Cefquinome Enrofloxacin Colisitin --> only after AB susceptibility test
36
Why should we be careful with gentamycin in E.Coli infections
E.Coli strains can easily develop resistance against gentamycin
37
What causes ileitis in swine?
Lawsonie intracellularis
38
3 main causes of Polyserositis
Glässer's disease - haemophilus suis Mycoplasma hyorhinis Staphylococcus suis
39
which ab is effective against all 3 causes of polyserositis in swine?
Florphenicol
40
Which AB are effective against Glässers and Mycoplasma hyorhinis?
OTC , DOX
41
Which are the best AB against Polyserositis in Swine, but are CIA?
Ceftiofur Cefquinome Enrofloxacin
42
PRCD - porcine respiratory disease complex causes
- actinobacillus pleuropneumonia - pasteurella multocida - bordetella bronchiseptica - glässerella parasuis - streptococcus suis - mycoplasma hyorhinis
43
Acute meningitis caused by
Streptococcus suis
44
Acute meningitis is caused by streptococcus suis, how is amoxicillin helping?
amoxicillin parenterally --> reach appropriate concentration in the liquor <=> due to damaged meniges
45
Mycoplasma Hyopneumoniae löst eine..
... bronchointerstitial pneumia aus
46
enzoonotic pneumonia
catarrhal - purulent or suppurative bronchopneumonia
47
Where can we find macroscopic lesion in case of mycoplasma hyopneumoniae?
apical cardiac intermediate diaphragmatic lung lobe
48
Which AB is the best against Mycoplasma hyopneumoniae? - tylvalosin - tylosin - doxycycline - tilmicosin
tylvalosin
49
Which AB is the best against Mycoplasma hyopneumoniae? - Lincomycin - Linco- spectino - Tulathromycine/gamitromycin - florfenicol
- Tulathromycine/gamitromycin
50
Which AB is the best against Mycoplasma hyopneumoniae? - Lincomycin - Linco- spectino - Tiamulin/valnemulin - florfenicol
Tiamulin/valnemulin
51
Which one is not active against Gram -, but against Myco? - tylvalosin - tilmicosin - tylathromycin
Tylvalosin
52
Which one is active against Gram -, Myco hyopneumonia and APP? - tylvalosin - tilmicosin - tulathromycin
tulathromycin/ Gamithromycin | rapid absorption from inj, extensive diffusion to tissues, slow elimination
53
Which one is variably active Myco hyopneumonia, but active against APP and pasteurella multocida ? - tylvalosin - tilmicosin - tulathromycin
Tilmicosin
54
How old are swines infected by Actinobacillus Pleuropneumonia? - 0-4 weeks - 4-8 weeks - 8-12 weeks - >12 weeks
8- 12 weeks old
55
Best Ab choice in case of actinobacillus pleuropneumoniae (APP) - Amox - Amox - Clav - Ceftiofur - Cefquinome
Amox (>80%)
56
Best Ab choice in case of actinobacillus pleuropneumoniae (APP) - Amox - PotSA - none - both
both
57
Which drugs have an outstanding effect against actinobacillus pleuropneumoniae, but should be used as last resort?
Fluoroquinolones + 4G cephalosporines | Enrofloxacine & Marbofloxacin
58
Which drugs have a good effect against APP, but should be used as last resort, after susceptibilty test?
Tetracyclines --> frequent resistance
59
Symptomatic treatment of MMA, PDS with which drugs?
Meloxicam & flunixin - antiendotoxic effect
60
Gentamycin absorble in gut? - yes, good absorption - no, no absorption in gut
no --> im
61
Which drug is eliminated by milk? - amox + clav - gentamycin - florphenicol
florphenicol --> damage for piglets
62
which drug cannot be used in lactating sows, if there is a MMA, PDS? - amox + clav - gentamycin - florphenicol
florphenicol
63
Which is the best drug in case of E.coli caused PDS/MMA? - amox + clav - gentamycin - florphenicol
amox + clav gentamycin -- no abs in gut florfenicol -- excretion by milk
64
Which drug cannot be used in E.Coli cause PDS/MMA? - Colistin - Fluoroquinolones - 3&4 gen Cephalosporins
Colistin --> not absorbed by gut after po & parenteral cause many side effects
65
What do we need to do if we want to use 3&4 gen Cephalosporins in case of E.Coli caused PDS/MMA?
prove bacteria is resistant to cat.D&C | prove bacteria is susceptible to category B
66
Which one has a good effect against Gram - and Gram + bacteria ? - Fluoroquinolones - 3&4 gen Cephalosporins - both - none
both
67
Age swine in case of Staphylococcus Hyicus infection? - suckling - weaned - suckling and weaned
suckling and weaned
68
Can we use Amox against staphylo hyicus?
no, because they produce beta lactamase
69
3 best drugs against staphy hyicus?
tylosin lincomycin PotSA
70
Can we use amox + clav in staph hyicus?
yes, it is active but need high concentration to reach the skin
71
Erysipelothrix rhusiopathiae occurs: - upper airway - lower airway - both
upper resp tract
72
Against which drugs are Erysipelothrix rhusiopathiae always susceptible? - penicillin - amox - both
both
73
Mycoplasma hyosynoviae causes arthritis in swine, which drugs reaches the appropriate concentration in the synovia?
Tylvalosin Tulathromycin Gamithromycin Florfenicol

Prudent use (3 decks)

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