Ab Spectrum Quiz Flashcards

1
Q

Penicillins

A

Penicillin V

Penicillin G

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2
Q

Coverage for Penicillins

A

Surfers hand Y
Streptococcus (Pyrogenes, Viridans &some Pneumo), Treponema palidium (SYPHILIS),
some staph

Enterococcus faecalis

Very little N. meningitidis

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3
Q

Drug of choice for Syphilis

A

Penicillin G

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4
Q

Antistaphylococal Penicillins

A

Nafcillin
Dicloxacillin

There is added protection here against beta-lactamases to enhance staphylococcal coverage

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5
Q

Antistaphylococcal Penicillins have coverage for…

A

BABY SHARK HAND
MSSA (Staph Aureus)
Staph epi
Streptococcus (S. pneumoniae, pyogenes)

NOT ACTIVE AGAINST MRSA, ENTEROCOCCI, ANAEROBES

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6
Q

Nafcillin

A

Nafcil

Antistaphylococcal Penicillin

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7
Q

AmiNOpenicillins

A

Ampicillin

Amoxicillin

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8
Q

Aminopenicillin coverage…

A

LEFT HAND L

E. faecalis
PCN resistant S. Pneumo
S. pyogenes

N. meningitidis
H. Influenzae

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9
Q

HEN PEKS

A
H. Influenzae
Enterobacter aerogenes
N. meningitidis
Proteus mirabilis
E.Coli
Klebsiella
Serratia marcescens
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10
Q

Ampicillin is DOC for…

A

E. faecalis

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11
Q

Aminopenicillins are 1st line for…

A

Otitis media

and DOC for endocarditis prophylaxis

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12
Q

Aminopenicillins + Beta Lactamase Inhibitors are different from just Aminopenicillins because…

A

Gram Neg (HEN PEKS), with added Anaerobic coverage, and MSSA

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13
Q

Aminopenicillins +Beta Lactamase Inhibitors

A

Ampicillin/sulbactam

Amoxicillin/clavulanate

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14
Q

Amoxicillin/clavulanate Brand Name…

A

Augmentin

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15
Q

Ampicillin/sulbactam Brand name…

A

Unasyn

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16
Q

Aminopenicillins+Beta Lactamase Inhibitor coverage…

A
HEN PEKS
Bacteroides fragilis
Staph aureus(MSSA)
S.Pneumoniae
S. Pyogenes
Enterococcus
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17
Q

Ampicillin/sulbactam is a great drug to tx..

A

Enterococcus

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18
Q

Piperacillin/Tazobactam Class

A

Antipseudomonal PCN + B lactamase inhibitor

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19
Q

Piperacillin/Tazobactam Brand

A

Zosyn

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20
Q

Piperacillin/Tazobactam coverage…

A

Covers everything except E. faecium & MRSA

PRIMARILY USED FOR PSEUDAMONAS

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21
Q

Really important Tx for MRSA…

A

Vancomycin

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22
Q

The ONLY Cephalosporin to cover MRSA…

A

Ceftaroline

TEFLARO

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23
Q

1st Generation Cephalosporins cover mostly…

A

Gram Positives

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24
Q

2nd Gen Cephs cover mostly…

A

GPs with few GNs

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25
3rd Gen Cephs cover..
Mainly GNs | Ceftazidime covers Pseudos
26
4th Gen Cephs cover...
Mainly GNs | Cefepime covers Pseudos
27
1st Generation Cephalosporins...
Cefazolin Cephalexin Cefadroxil
28
1st gen Ceph coverage....
MSSA Staph Strep Very little coverage: Proteus E. Coli Klebsiella 3 fingers
29
Cefazolin is mostly used for....
Pre-Op Prophylaxis
30
2nd Generation Cephs...
``` Cefuroxime Cefoxitin Cefotetan Cefprozil Cefaclor ```
31
2nd gen cephs that have activity against Anaerobes..
Cefotetan Cefoxitin are both active against B.fragilis TAN FOX**
32
2nd Gen Cephs "Claim to Fame"
H. Influenza
33
Coverage of 2nd Gen Cephs...
``` 4 finger S. pyogenes S. Pneumoniaa MSSA H.Influenza N. Meningitidis P. mirabilis E. coli Klebsiella spp. ```
34
2nd Gen TAN FOX coverage...
5 fingers | Expanded to include Anaerobe--> B. fragilis
35
Cefotetan Brand Name and Class...
Cefotan | 2nd gen ceph
36
Cefoxitin Brand name and Class...
Mefoxin | 2nd gen ceph
37
3rd Gen Cephs...
Cefotaxime Ceftriaxone Ceftazidime Ceftazidime/Avibactam ``` Cefixime Ceftibuten Cefditoren Cefpodoxime Cefdinir ```
38
3rd Gen Ceph coverage...
``` 5 fingers S.Pneumoniae S. Pyogenes MSSA Enterobacter spp H. influenza N. meningitidis Proteus mirabilis E.coli Klebsiella Serratia ```
39
Ceftriaxone Brand and class...
Rocephin 3rd gen ceph Good BBB tx for meningitis
40
Ceftazidime Brand and class...
Fortaz - Different from the other 3rd gens because it covers Pseudomonas - Very little GPC
41
CAPES Bacteria
``` Citrobacter Acinetobacter Pseudomonas Enterobactr Serratia ```
42
Ceftazidime/avibactam coverage...
Pseudomonas CAPES -Loses most of GPC 3rd gen ceph Ceftazidime ALONE is good for Pseudomonas as well
43
Ceftriaxone is DOC for..
gonorrhea
44
4th generation Cephs...
Cefepime
45
Cefepime coverage...
5 fingers, no faecalis, no MRSA, no anaerobes ``` Streps, MSSA, PEKS, N.Meningitidis, H.influenza, Enterobacter spp Pseudomonas CAPES *Acinetobacter* ```
46
5th gen cephs...
Ceftaroline | Ceftolozan/Tazobactam
47
Ceftaroline Brand...
Teflaro
48
Ceftolozan/Tazobactam Brand...
Zerbaxa
49
Ceftaroline coverage...
5 finger Including MRSA Not including Faecalis
50
Ceftolozane/tazobactam coverage...
Strep PSEUDOMONAS And more
51
Which Cephs cover Pseudomonas??
CeftaziDIME CeftaziDIME/avibactam CefePIME CeftoloZANE (w/or w/o Tazobacatm)
52
Monobactam class contain..
Aztreonam
53
Monobactams coverage...
NO GPC All GN, including Pseudo HENPEKS & Pseudo
54
Carbapenems...
Impinem/cilastatin Ertapenem Meropenem Meropenem/Vabobactam
55
Carbapenems coverage...
6 fingers! | NO MRSA
56
All carbapenems have Pseudo coverage except...
Ertapenem
57
Carbapenems cover SO much but they don't include
VRE, MRSA, or LMC
58
Ertapenem is different from the others in its class because it doesn't cover...
E. faecalis, or Pseudo
59
Vancomycin class & brand...
Glycopeptide VANCOCIN
60
Vancomycin coverage..
``` ALL GPC Especially Staph (MRSA) Strep Enterococci Corynebacterium C. Difficile ```
61
Telavancin class and brand...
Lipoglycopeptide VIBATIV
62
Telavancin coverage...
MSSA MRSA Strep Vanco-resistance F. faecalis
63
Daptomycin class and brand...
Cyclic Lipopeptide CUBICIN
64
Dapto coverage...
GPC Staph (MRSA AND VRSA) Entercoccie INCLUDING FAECALIS AND FAECIUM *Doesn't treat Pneumonia*
65
Class that has really good AtYpical coverage...
Macrolides Erythromycin Clarithromycin Azithromycin Fidaxomicin
66
Oral macrolide for C.diff ONLY
Fidaxomicin | DIFICID
67
Macrolide coverage...
``` MSSA S. Pneumoniae S. viridans &pyogenes Listeria Haemophilus H. flu M.catarrhalis Bordetella Neisseria Shigella ``` IMPORTANT Legionella Chamydia Mycoplasma
68
Azithromycin Brand
Zithromax Macrolide
69
Clarithromycin
Biaxin Macrolide
70
Erythromycin
E.E.S Macrolide
71
Aminoglycosides...
``` Amikacin Tobramycin Gentamicin Streptomycin Neomycin Plazomicin ```
72
Aminoglycoside coverage...
``` Gram+ Staph Gram- Pseudo Proteus Serratia ```
73
Tetracyclines...
Tetracycline Doxycycline Minocycline
74
Minocycline brand and coverage info....
Minocin DOC CA-MRSA
75
Tetracycline coverage...
``` MSSA Strep Enterococci Nocardia Bacillus Propionibacterium ``` haemophilus Moraxella chlamydia ``` ATYPICALS Spirochetes Rickettsiae Bacillus anthracis Treponema pallidum ```
76
Glycyclcline coverage...
``` BROAD Most streps MSSA MRSA* VRE ``` H.flu Klebsiella Clostridium Bacteroides Chlamydia Legionella Mycoplasma
77
Oxazolidinone class
Linezolid | Tezolid
78
Linezolid & Tezolid coverage...
Similar to Vanc MRSA** S pneumo VRE*
79
Quinolones class
Ciprofloxacin Levofloxacin Moxifloxacin
80
Quinolones coverage....
E faecalis Strep MSSA Listeria H. flu Moraxella Neisseria PSEUDO Chlamydia Legionella Mycoplasma
81
Quinolones with enhanced activtiy against strep pneumo and atypicals....
Moxi Gemi Levo
82
Quinolone for MRSA
Delafloxacin
83
Important sulfonamide
Sulfamethoxazole/trimethoprim
84
Sulfamethoxazole/trimethoprim brand
Bactrim
85
Bactrim coverage...
``` Most GPC MRSA CA-MRSA Strep no GAS Listeria Nocardia ``` ``` Stenotrophomonas Haemophilus Proteus E.coli Klebsiella Enterobacter Shigella Salmonella ``` Toxoplasmosis parasite
86
Important Lincosamide..
CLINDAMYCIN
87
Clindamycin coverage...
Strep & Staph CA-MRSA Anaerobes like B FRAGILIS*
88
Clindamycin brand name
Cleocin
89
Metronidazole mainly covers..
C. Diff | Protozoa (giardiasis, gardnerella, amebiasis, trichomonas)
90
Fidaxomicin
Dificid
91
Approved tx for C. Difficile
Dificid
92
Nitrofurantoin description
Urinary Antiseptic | ONLY for lower UTI tx
93
Nitrofurantoin coverage...
S. aureus Enterococcus VRE E. coli Klebsielle Enterobacter