Abnormal WBC count Flashcards
1
Q
causes of neutrophilia
A
- CML
- Physiological- exercise pregnancy, lactation, neonates
- acute infection
- acute inflammation
- drugs: steroids, G-CSF
- Leukocyte adhesion deficiency
- smoking (number one cause)
2
Q
neutropenia
A
- physiologic: more common in AA
- drugs: antipsychotics, anti-epilieptics, anti-thyroid, antibiotics
- chemo
- immune: lupus, rheumatoid arthritis
3
Q
agranulocytosis
A
almost always drug induced:
- clozapine (anti psychotic)
- propythiouracil (antithyroid)
- anti convulsant
- sulfa and chloramphenicol
- levamisol cocaine (most common in ER)
4
Q
eosinophilia
A
NAACP: Neoplasm Allergy/asthma Addisons/athero embolic Collagen vascular disease Parasites
5
Q
basophilia
A
hypersensitivity
myeloproliferative*
thyroid disease
6
Q
lymphocytosis
A
- viral infections
- CLL
- lymphomas and waldenstroms
7
Q
lymphopenia
A
- immunodeficiencies- HIV/AIDS
- immunosuppressive drugs including steroids
- lymphomas
- granulomatous diseases
- alcoholism, malnutrition, Zn deficient
8
Q
monocytosis
A
MDS
9
Q
acquired defects of PMN fn
A
- steroid use
- alcoholism
- leukemias
- MDS
- MPD
