ABO Flashcards

(59 cards)

1
Q

ABO forward reverse grouping test must be done on

A

donors and patients

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2
Q

what is considered to be the major blood group

A

ABO blood group

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3
Q

what is the most frequently performed test in the blood bank

A

ABO bloo group system

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4
Q

Naturally occuring bodies

A

ABO blood group system

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5
Q

what is described by bernstein

A

inheritance of the ABO blood group

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6
Q

when was inheritance discovered by bernstein

A

1924

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7
Q

the inheritance of what genes follows mendelian genetics

A

ABO genes

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8
Q

what terminology if you inherit both A and B genes, threfore you will have AB antigens

A

CODOMINANT

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9
Q

WHAT gene IS CONSIDERED AN AMORPH

A

O genes

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10
Q

no detectable antigen is produced in response to the inheritance of these genes

A

amorph

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11
Q

what blood type are phenotype

A

blood type A, blood type B, blood type O

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12
Q

what are the genotypes

A

AA,AO,BO,OO

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13
Q

First to discover the human blood group system

A

Karl Landsteiner

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14
Q

Individual who first performed the forward and reverse grouping

A

Karl Landsteiner

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15
Q

LANDSTEINERS LAW

A
  1. The antigen on the RBC determines the blood group
  2. The corresponding antibody is never found in the individuals serum
  3. the opposite antibody is always present in the individuals serum
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16
Q

what antibody is naturaly occuring

A

ABO Antibodies

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17
Q

PREDOMINANTLY IgM

A

ABO antibodies

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18
Q

what is the exception in the ABO antibodies which is IgG in nature

A

anti-AB

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19
Q

why should we not perform reverse groupin on babies

A

production of ABO is not yet high

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20
Q

Detectable titers in ABO atibodies

A

3 to 6 months

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21
Q

what is the peak of ABO antibodies

A

5-10 years

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22
Q

what causes rapid intravascular hemolysis

A

ABO antibody

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23
Q

what antibody is produced by blood group A, B, AB,O

A

ANTI-B, ANTI-A, NONE, ANTI A, ANTI B, ANTI AB

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24
Q

CAN WE PERFORM FORWARD TYPING ON BABIES

25
ABO ANTIGEN IS ALREADY AVAILABLE IN FETUS ON WHAT DAY
37TH DAY OF FETAL LIFE
26
WHAT ANTIGENS IS DEVELOPED FROM PRECURSOR H SUBSTANCE
A ANTIGEN B ANTIGEN
27
SPECIMEN FOR BLOOD TYPING
SALIVA, PANCREATIC SECRETION, GASTRIC SECRETION
28
WHAT IS THE MOST COMMON BLOOD TYPE
O AND A
29
RAREST BLOOD TYPE
AB (ROYAL BLOOD)
30
WHAT ARE THE ANTIGEN PRESENT IN BLOOD TYPE A,B,AB,O
A and H B and H AB and H O and H
31
Result from the interaction of genes of three separate loci
ABO, H, Se
32
precursor structure on which A and B are made
H antigen
33
what gene are closely linked and are located on chromosome 19
H and Se gene
34
ABH antigen precursor in type 2 substance
RBC
35
ABH antigen in type 1 precursor substance
secretions
36
what is the enzyme in the formation of H ANTIGEN
alpha-2-L fucosyltransferase
37
what is the sugar present in the formation of A antigen
N-acetyl d-galactosamine
38
what is the sugar present in the formation of the B antigen
d-galactose
39
what is the product of alleles at ABO and Hh loci
Secretor gene
40
how many percent of the population is secretors
80 percent
41
sese or SESE are the individuals that are non secretors
sese
42
wht are the fluids in which A,B, AND H substance can be detected in secretors
1. saliva 2.tears 3.urine 4.digestive juices 5.bile 6.milk 7. amniotic fluid 8. pathological fluid
43
seed extract that agglutinate human cells with some degree of specificity
lectin
44
genotype of blood group O
OO
45
Anti H antisera
ulex europaeus
46
blood group A genotype
A, H
47
LECTIN of Blood group A
dolichos biflorus
48
what antigen is capable of crossing the placenta
IGg
49
antigen of blood group A
A,H
50
antibody of bloo group A
anti-B
51
genotype of blood group B
B,H
52
Bandeiraea simplicifolia is revised to
Griffonia simplicifolia
53
what is the genotype of blood group AB
AB
54
antibodies in blood group AB
none
55
why is H very little in the antigen of blood group AB
because there is already 2 sugars added to the original structure
56
greatest amount of reactiviy to the least amount
0>A2>B>A2B>A1>A1B
57
recessive gene in bombay phenotype
hh
58
also called OH phenotype
Bombay phenotype
59
appears as group O on forward typing
Bomby phenotype