ABSITE-Infection

Question 1

MC organism in SSI

Answer 1

Staph aureus

Question 2

MC organism in VAP and nosocomial PNA

Answer 2

Staph aureus

Question 3

Orgs cause toxic shock syndrome?

Answer 3

Staph. aureus, Strep. pyogenes - exotoxin

Question 4

Orgnism responsible for scalded skin syndrome

Answer 4

Staph aureus

Question 5

What organisms exude an exoslime biofilm?

Answer 5

S. aureus and S. epidermidis

Question 6

What enables Staph aureus to be resistent to PCNs?

Answer 6

beta lactamase

Question 7

How do you treat S. aureas resistant to PCNs?

Answer 7

Anti-staph PCN: e.g. oxacillin, dicloxacillin

Question 8

What makes MRSA resistant to methicillin?

Answer 8

Th ePCN binding protein has been altered

Question 9

What % of pop are carriers of MRSA?

Answer 9

20%

Question 10

What prevalent Staph is coag-? Coag+?

Answer 10

Coag-: S. epidermidis. Coag+S. aureus

Question 11

MC organism inline infections and catheter-related blood stream infections?

Answer 11

S. epidermidis

Question 12

What org. is the most frequent contaminant in blood cultures?

Answer 12

S. epidermidis

Question 13

What infections does Strep pneumoniae cause?

Answer 13

PNA, bacteremia, septic arthritis, endocarditis, cellulitis

Question 14

Give MC organisms responsible for necrotizing fasciitis

Answer 14

Strep pyogenes

Question 15

MC org involved in endocarditis

Answer 15

Strep sanguinous

Question 16

Bugs that cause endocarditis

Answer 16

Strep -viridans, -bovis, -sanguinous, -mitis

Question 17

Enterococcus faecalis is resistant to what class of abx?

Answer 17

cephalosporins

Question 18

What % of population has Enterococcus in the gut?

Answer 18

95%

Question 19

What infections are associated with Enterococcus

Answer 19

UTI, bacteremia, endocarditis, diverticulitis

Question 20

What causes VRE to be resistant to vancomycin?

Answer 20

Mutation in cell wall binding protein

Question 21

Are Clostridia aerobic or anaerobic?

Answer 21

Anaerobic

Question 22

Is Clostridium difficile ever a normal org of the colon?

Answer 22

Yes. 5% are carriers

Question 23

What org causes gas gangrene and emphesematous cholecystitis?

Answer 23

Glostridium perfringens

Question 24

What org causes tetanus?

Answer 24

Clostridium tetani

Question 25

What infections do Corynebacteria cause?

Answer 25

Endocarditis, line infections, cellulitis, granulomatous mastitis

Question 26

MC organism in gut

Answer 26

Bacteroides fragilis

Question 27

MC anaerobe in gut

Answer 27

Bacteroides fragilis

Question 28

MC organism in anaerobic peritoneal infections

Answer 28

Bacteroides fragilis

Question 29

MC facultative GNR in gut

Answer 29

E. coli

Question 30

MC organism in UTI

Answer 30

E. coli - 90%

Question 31

MC org in biliary tract infec (cholangitis)

Answer 31

E. coli

Question 32

MC org in pyogenic liver abscesses

Answer 32

E. coli

Question 33

What E. coli type causes food poisoning or HUS?

Answer 33

O157:H7

Question 34

MC org in struvite nephrolithiasis

Answer 34

Proteus mirabilis

Question 35

What org produces urease?

Answer 35

Proteus mirabilis

Question 36

MC lung infection w/ cystic fibrosis?

Answer 36

Pseudomonas aeruginosa

Question 37

MC organism in burn wound infections?

Answer 37

Pseudomonas aeruginosa

Question 38

MC colonizer of indwelling catheters?

Answer 38

Pseudomonas aeruginosa

Question 39

What org produces an alginate mucoid layer?

Answer 39

Pseudomonas aeruginosa

Question 40

Why is Pseudomonas aeruginosa difficult to treat?

Answer 40

Low abx susceptibility and can undergo acquired resistance during abx tx.

Question 41

What is the best treatment for Acinetobacter baumannii?

Answer 41

Carbapenems

Question 42

What org frequently colonizes ETT, trachs and central lines?

Answer 42

Stenotrophomonas maltophilia

Question 43

Why is Stenotrophomonas maltophilia difficult to treat?

Answer 43

Naturally resistant to many abx, including carbapenems

Question 44

What org is a contraindication to lung transplant in some centers?

Answer 44

Burkholderia cepacia

Question 45

What infection is associated with PNA in COPD pts?

Answer 45

Moraxella catarrhalis

Question 46

Give # of org and classes of org in: stomach

Answer 46

Almost sterile, few GPCs, some yeast

Question 47

Give # of org and classes of org in: proximal small bowel

Answer 47

10^5 bacteria, mostly GPCs

Question 48

Give # of org and classes of org in: distal small bowel

Answer 48

10^7 bacteria, GPCs, GPRs, GNRs

Question 49

Give # of org and classes of org in: colon

Answer 49

10^11 bacteria, 99% anaerobes, few GNRs and GPCs

Question 50

MC bacterial class (e.g. aerobes, anaerobes) in GI tract

Answer 50

Anaerobes (e.g. bacteroides, and Clostridium)

Question 51

MC org overall in GI tract

Answer 51

Bacteroides fragilis

Question 52

MC anaerobe in colon

Answer 52

Bacteroides fragilis (30%)

Question 53

Anaerobes outnumber aerobic bacteria in what proportion?

Answer 53

1000:01:00

Question 54

Why do anaerobes require a low O2 environment?

Answer 54

They lack superoxide dismutase and catalase - vulnerable to reactive O2 species

Question 55

What is the most potent stimulant for TNF-alpha release

Answer 55

Lpid A in LPS (endotoxin) from GNR

Question 56

MC time frame for atelectasis

Answer 56

POD 1-2

Question 57

MC time frame for UTI

Answer 57

POD 3-5

Question 58

MC time frame for DVT

Answer 58

POD 4-6

Question 59

MC time frame for wound infection, medications

Answer 59

POD 5-7

Question 60

MC time frame for an abscess to develop

Answer 60

POD 7-10

Question 61

What organisms can cause a fever in 48 hours?

Answer 61

C. perfringens or group A beta hemolytic strep

Question 62

Define when a nosocomial infection can occur?

Answer 62

48 hours after admission or up to 30 days after discharge

Question 63

What % of nosocomial infections can be prevented?

Answer 63

35%

Question 64

MC nosocomial infection?

Answer 64

UTI

Question 65

What % of nosocomial UTIs are due to E. coli

Answer 65

80%

Question 66

What group of pts have the highest risk of developing a nosocomial infect?

Answer 66

Burn patients: UTI, VAP, CRBSI