ABSITE QUEST Flashcards

(213 cards)

1
Q

What would a FDR need to have to warrant your screening at age 40 vs age of onset in FDR (whichever is earlier)?

A

advanced adenoma (high-grade dysplasia, >/= 1 cm, villous or TV histology, traditional serrated adenoma)
OR
advanced sessile serrated polyp (>/= 1 cm, any dysplasia)

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2
Q

most likely injured vessel during ALIF (esp L5-S1)

A

left common iliac vein

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3
Q

best imaging for initial w/u of extremity soft tissue sarcoma?

A

MRI - depth and anatomic relationships

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4
Q

What does PCC contain?
Why not FFP?

A

Clotting factors 2, 7, 9, 10
FFP takes too much volume and time

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5
Q

Mgmt for chylous ascites?

A

MCFA –> bowel rest, TPN, octreotide –> surgical ligation

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6
Q

MAP target in septic shock?

A

65

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7
Q

what is considered cost effective per CDC?

A

cost of intervention <$50,000 per QALY (quality-adjusted life years gained)

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8
Q

What is Hinchey classification?

A

0: mild
IA: pericolic inflammation - phlegmon
IB: pericolic/mesocolic abscess
II: pelvic, distant intraabd or intraperitoneal abscess
III: purulent peritonitis
IV: feculent peritonitis

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9
Q

How does ketamine work

A

Noncompetitive NMDA receptor antagonist that blocks glutamine

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10
Q

Which nerves innervate EAS?

A

internal pudendal (inf rectal)
S4

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11
Q

In which perianal spaces can a horseshoe abscess form

A

ishiorectal
intersphincteric

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12
Q

What is the modified hanley procedure? (for horseshoe abscesses)

A

small incision bw tip of coccyx + anal verge
separate tissues of EAS, drain abscess
seton around sphincter complex
2 lateral counterincisions are made with setons added as well

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13
Q

treatment for supralevator abscess

A

image-guided closed suction drain placement

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14
Q

What type of anastomosis is avoided in pts with hx diarrhea

A

coloanal, low colorectal, or ileoanal anastomoses

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15
Q

what’s a full workup for CRC?

A

CEA
CT C/A/P
Cscope

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16
Q

what timeframe constitutes a CHRONIC anal fissure

A

6 wks

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17
Q

Ideal diet for chylous ascites?

A

high protein
low fat
OR TPN +/- somatostatin

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18
Q

describe immune infiltrate of chylous ascites

A

leukocytosis with lymphocytic predominance

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19
Q

what levels are high in carcinoid syndrome?

A

5-HIAA
serum chromogranin A

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20
Q

tx for metastatic carcinoid?

A

(in no order)
1. IR embo
2. surgical debulking
3. ss analogs ie lanreotide
if don’t work alone, can add a tryptophan hydroxylase inhibitor
4. chemo

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21
Q

which cells do carcinoid originate from?

A

enterochromaffin or kulchinsky cells

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22
Q

__ to __% of carcinoids are found in the lung

A

10-25%

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23
Q

MC tumor of appendix?

A

carcinoid

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24
Q

GIST are MC found in the ___

A

stomach

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25
what do you do for mesenteric cysts?
must excise to prevent recurrence + malignancy risk - usually don't need SBR or resection of mesentery but ok to do if very large and compromising mesenteric vasculature
26
abx for pancreatic necrosis?
carbapenem alone (erta, imipenem) quinolone/ceftaz/cefepime + metronidazole
27
in which case would you be ok with FLR... <20% <30% <40%
- healthy liver - hepatic fibrosis + hepatotoxic chemo - cirrhosis
28
what's assoc with seatbelt sign?
Chance fracture - horizontal fx from post to ant, involving at least 2 columns (can have paraplegia)
29
what are obligate glucose users?
RBC peripheral neurons neutrophils adren medulla
30
what's a rare but serious complic of rubber band hemorrhoidectomy?
perianal sepsis tx: EUA with wide debridement + drainage
31
what kind of org is e coli
aerobic GN rod
32
MC bacteria in SBP?
1. e coli 2. streptococcus anaerobic = uncommon
33
where does medullary thyroid CA originate?
parafollicular C cells of thyroid
34
Rome IV criteria for IBS?
recurrent abd PAIN at least 1 day/wk in last 3 months, w/ 2+ of the following: - related to defecation - change in freq of stool - change in form (appearance) of stool *sx onset at least 6 mo prior to dx
35
Preop RF for anastomotic leak
male gender higher ASA class preop radiation renal disease most signif: fecal contamination (also excess intraop blood loss, >100)
36
which direction does appendix go with pregnancy?
more anterior imaging: US ... MRI if US can't see tx: lap appy (perf appendicitis assoc with 36% chance fetal loss!)
37
Characteristics of ACC?
irregular, heterogenous dia >4cm >20 HU <50% washout in 10 min (delay) hypointense compared to liver on T1 MRI
38
in a patient with leg venous insuff / post-thrombotic syndrome ... what do you do and why?
LE venogram to assess whether venous system (particularly proximally, like iliac) is chronically diseased or stenotic ... can stent to improve swelling
39
MC indication for hysterectomy?
symptomatic uterine fibroids
40
what is staining of desmoids?
beta catenin actin vimentin negative for: - cytokeratin - S100
41
serum chloride:phosphate ratio should be WHAT for primary hyperPTH?
>33
42
s & s of richter hernia?
tenderness + nodularity at surgical scar site ... progress quickly to bowel gangrene
43
in setting of dehydration, what happens to the efferent (renal) arteriole?
vasoconstriction to maintain glomerular capillary hydrostatic pressure --> maintain normal GFR
44
what is JGA pathway?
macula densa cells (within JGA) sense low Na --> JGA cells release renin --> activate RAAS --> increase Na + H20 reabsorption
45
types of fundoplication issues
normal nissen (360): could be too tight partial: maybe not tight enough *disrupted: recurrent symptoms (heartburn, regurgitation) twisted: chest pain, dysphagia, poss GOO *migrated: won't really see it and will see hernia (hole) *slipped: will see it + hernia (hole) PEH: will see clearly *likely one of these if having issues 2 months after surgery
46
what are the chances of siblings being HLA-identical?
25%
47
only NOA that can be partially removed via HD?
dabigatran
48
reversal for rivaroxaban? (xarelto)
andexanet alfa
49
mechanism of action: warfarin
prevent vit K decarboxylation of glutamic residues on vit-K dep factors
50
screening for FAP pts
*start CRC screening at age 12 - with flex proctosig ... +polyps --> Cscope -polyps --> repeat q1-2 years *start UGI tract screening at 20-25 yrs *annual thyroid screening
51
women with lynch syndrome ... when offer TAH BSO?
at time of colectomy, over 40 yrs, or have finished childbearing
52
where are carcinoids most likely found?
small intestine rectum appendix (if <2cm: appy alone ... if >=2cm, involving base, high risk, +LVI: stage --> R hemi + LAD)
53
tell me about vasopressin (sorry)
V1: vasoconstriction V2: water R V3: release of vWf and F8 - released from post pit but made in HYPOTHAL -ADH stimulated by hypovaolemia and hyperosmolarity
54
how does p53 work?
tumor suppressor protein cells with DNA damage --> cell cycle arrest --> DNA repair OR apoptosis
55
how does bacitracin work
inhibits bacterial cell wall synthesis side effects: nephrotoxicity (oliguria + edema) allergic contact dermatitis
56
what lung volume decreases with morbid obesity?
*decreased in chest wall + lung compliance - FRC (primarily due to decreased ERV) - VC - TLC
57
how do antifungals work?
amphotericin B: bind to fungal cell wall sterols --> cause lysis azoles: inhibit fungal cell wall synthesis (critical for cell wall growth) echinocandin (caspofungin): inhibit fungal cell wall synthesis
58
how does succinylcholine work?
noncompetitive neuromuscular ACh inhibitor ... binds to nicotinic R and causes depol
59
which is LESS likely to strangulate? direct or indirect hernia
direct hernia - wider neck
60
odontoid fx (C2)
type 1: upper part of dens - stable type 2: base of dens - unstable type 3: extend into C2 vert body - rarely need surgery
61
surgical procedure for slow transit constipation?
TAC with iliorectal anastomosis (50-100% success for increasing stool frequency)
62
causes of acute lower GI bleeding?
Anatomic (diverticulosis) Inflammatory (IBD) Neoplastic Vascular (angiodysplasia, radiation-induced, ischemia) Iatrogenic (polypectomy)
63
diverticulosis in high risk pt (persistent bleeding, old, anemia, elevated BUN) ... what do you do?
resuscitate --> bowel prep + Cscope asap (within 24 hr)
64
what is the pathophysiology that can lead to rapid death in open ptx?
collapsed lung 2/2 exposure to atmospheric air, causing severe alteratino of ventilation and venoarterial shuting (V/Q imbalance, respiratory distress)
65
tell me about ischemic orchitis after inguinal hernia surgery
- presents POD 2-5 (can last up to 12 wks) - ESP during surgery for RECURRENT inguinal hernia - thrombosis of pampiniform plexus >>> ligation of testicular artery - tx: anti-inflammatories (NSAIDs) + analgesics (ing nerve block for pain) *seldom need orchiectomy *do not re-explore *do no I&D
66
changes with alk or acidosis with breathing
hyperventilation --> hypoCO2 --> resp alkalosis hypoventilation --> too much CO2 --> resp acidosis
67
what is chronic inguinodynia
postop pain >3 mo after ing hernia repair tx: 1) PT + oral p meds 2) nerve block 3) respond to block but then have recurrent pain --> triple neurectomy (also remove tacks/mesh after lap surgery ; remove old mesh and replace in preperitoneal space after open surgery)
68
where are the inguinal nerves located
iliohypogastric: (lies on ant surface of quadratus lumborum and traverses iliacus) between ext and int oblique ilioinguinal: (traverses the iliacus) over the spermatic cord fem branch of gf nerve: (more medial course) underside of spermatic cord structures
69
how is protamine dosed?
1mg for every 100u heparin pt received (half life of heparin is 60-90 min, so also depends on time since heparin was dosed)
70
can everyone get protamine?
it's a component of insulin, so diabetics using NPH or insulin aspart protamine may have sensitivity
71
what meds can cause histamine release?
muscle relaxants opioids + ketamine abx (cipro, rifaximin)
72
preferred method of ureteral repair
- debride tissue - sptatulated anastomosis with interrupted absorbable sutures - double J stent - cover with vitalized tissue when possible - foley
73
what decreases risk of electromagnetic interference in pts with implantable cardiac devices?
*ultrasonic devices - cutting mode - bipolar > monopolar
74
where does indirect inguinal hernia sac lie, relative to spermatic cord?
anterior and medial
75
what are alkylating agents
oxaliplatin carboplatin cyclophosphamide
76
what kind of testicular tumor has elevated AFP?
NONseminomatous
77
indications for STAT C section
- mother in cardiac arrest - placental abruption (+/- vag bleeding, +pain) - nonreassuring fetal HR (severe bradycardia 70-80 or sinusoidal pattern)
78
normal distance bw rectus muscles
1-2cm
79
pharmacologic intervention for dumping syndrome?
- acarbose (slows carb digestion) - octreotide
80
primary lymphoid organs (generate lymphocytes) secondary lymphoid organs (initiate adaptive immune response)
liver, bone, thymus LN, spleen, tonsils, adenoids, Peyer patches
81
Factor 9 deficiency ... what product can you give?
FFP (not Factor 9 concentrate)
82
Relative CI to PD catheter
peritoneal scarring physical/psych impairment anuria large pt size active inflamm process surgical ostomies VP shunt lg abd wall hernia
83
best way to fix an abd wall hernia in setting of peritoneal dialysis plan?
extraperitoneal mesh repair at time of PD catheter placement
84
what can cause intussusception after IgA vasculitis? Henoch Schonlein purpura
small bowel wall hematoma usually ileo-ileal intussusception (vs usual ileocolic)
85
MCC mortality in cardiac transplant pts after 1 year?
atherosclerosis
86
best diagnostic scan for colovesicular fistula
CT
87
how to fix a cardiac injury
pericardiotomy digital pressure fix w permanent (prolene) pledget'ed suture, horiz mattress
88
mechanism underling refeeding syndrome
sudden influx of phosphate into cells --> resumption of ATP (as aside: develop low K, Mg, Phos 2/2 intracellular shift 2/2 insulin)
89
rate control agent of choice for COPD (or bronchospasm)
CCB
90
usual tx for ac joint separation?
nonop w sling - rarely assoc w brachial plexus injury - clavicle --> ac jt --> acromion
91
MCC pseudomyxoma peritoneii?
appendix
92
best a/c in setting of HIT?
direct thrombin inibitors - argatroban (metab + excreted by liver) - bival (also metab by liver by excreted by liver + kidney... prefer for cirrhotics) - L FOR LIVER
93
HIT - immediate tx?
DC heparin start alternative a/c (usually direct thrombin inhibitor)
94
what can a slipped lap gastric band cause?
obstruction necrosis erosion * see fundus above band on UGI
95
MCC small bowel hemorrhage?
angiodysplasia
96
For a "biochemical leak" (not true fistula) of pancreas - drain removal?
provider dependent dont need to wait till amylase normal
97
TYPES OF PANC FISTULAS Biochemical leak Grade B - explain Grade C - explain
Grade B: - persistent drainage >3 wks - req interv Grade C: need OR for fistula, MOF, death
98
what is McVay repair?
anchor conjoint tendon to Cooper's ligament
99
MC pathogens for ventilator assoc PNA
Staph aureus Pseudomonas
100
which steroids for adrenal crisis?
IV hydrocortisone
101
where are primary bile acids conjugated?
hepatocytes
102
Explain bile acid life cycle once secreted
80% --> [conjug] absorbed in TI 15% --> deconguj --> absorbed via passive transport in colon 5% --> stool
103
what are the aminoglycosides?
-micin or -mycin
104
Risk of wound infection: clean clean contaminated contaminated dirty
1-5% 3-11% 10-17% >27%
105
what hemodynamic changes may you expect with high cervical injuries? (neurogenic shock)
*hypotension (2/2 art/venous vasodilation) + bradycardia *due to disruption of sympathetic flow along with unopposed vagal tone
106
what is spinal shock
loss of SC reflexes below level of injury
107
MC bacterial infection in cirrhotics
SBP (--> UTI --> PNA --> skin/soft tissue)
108
SBP findings + tx
ascitic PMN>500 usually single org (E coli) tx: 3rd gen cephalosporin like CTX
109
carcinoid syndrome - which metabolite test in best? which imaging test?
urine 5HIAA (>25 mg/day) 68Ga-DOTATATE PET/CT
110
where does carcinoid originate?
Kulchitsky cells (enterochromaffin cells)
111
issue with CgA for carcinoid?
can be falsely elevated by PPI use
112
duo ulcer >3cm in HD unstable pt - surgical tx?
controlled duodenal fistula pyloric exclusion gastrojejunostomy
113
how to calculate sodium deficit
(desired Na - pt's Na) x TBW TBW = 60% body wt in males VS 50% body wt in females
114
interferons
1. involved in antifungal + antiviral responses 2. pro-inflammatory 3. major cytokine of wound healing - promote RNA + protein production
115
Phase 1 wound healing - major cytokines? "I P M" (inflammation)
TNF-alpha IL-1 PDGF
116
Repaired esophageal atresia - most common longterm issue?
dysphagia
117
Under which Na will you give 3% regardless of volume status?
120
118
(1) Na<120 OR symptomatic with coma/convulsions (2) otherwise hyponatremic mgmt?
(1) 3% hypertonic saline (2) raise Na by 0.5 mEq/hr
119
absolute indication for surgery in NEC?
intestinal perforation
120
which artery is in NAVEL
COMMON femoral artery
121
what does femoral nerve do?
*straightens the legs!* hip flexion + knee extension
122
what is succinylcholine?
depolarizing, nicotinic ACh-R agonist rapid onset, short duration
123
CI to succ
severe extensive burns crush injury prolonged immobilization 48-72 hr after denervating injury (stroke, SCI) NMS disease (ALS, MD, MS) infection w/ toxin-production (tetanus, botulism) *severe hyperK --> V fib
124
do you need bx preop for HCC dx?
no
125
MC type of appendiceal cancer
NET
126
what if adenoCA is found incidentally in appendix after lap appy? tx?
R hemi
127
Thoracic outlet syndrome - neurogenic (MC - 90%) - venous - arterial Tx?
1. aggressive PT 2. rib resection + scalenectomy + brachial plexus dissection (+ cervical rib and C7 TP removal if needed) VENOUS: catheter-directed thrombolysis ... after, check for stenosis - if yes, that's indic for surgery (above) ARTERIAL: almost always C7 TP or cervical rib. Surgery = reect C7 abnormality + first rib + subclav artery resection/graft
128
what do you get with ... (1) craniopharyngioma (2) ependymoma (3) meningioma (4) cervical neuroblastoma
(1) bitemporal hemianopia (2) HA, v, visual loss, b/l babinski (3) seizure, sensory/motor deficits (4) Horner syndrome ("PAM") + neck mass
129
what are the only 2 aa that are not glucogenic and can be used for ketogenesis?
lysine leucine
130
what causes bradycardia during insufflation?
high flow rate CO2 --> peritoneal stretch --> strong+fast vagal response TRY: slowing insufflation rate O/W: convert to open
131
preferred conduit for CABG? MC used?
PREFERRED: internal mammary (thoracic) arteries - left --> LAD - right --> R coronary MC USED: GSV
132
vinyl chloride and arsenic --> which CA?
hepatic angiosarcoma
133
when use Wilcoxon signed-rank test?
nonparametric, paired group ordinal data (like #'s on a scale (survey etc)) can not be assumed to be normally distributed
134
MC presentation of ... internal hemorrhoids external hemorrhoids
internal: prolapse, bleed external: rupture of vein in inf hemorrhoidal plexus --> acute thrombosis
135
Tx for below internal hemorrhoids? grade 1 + 2 gr 2 + 3 gr 3 + 4
gr 1+2 = infrared coagulation; injection sclerotherapy gr 2+3 = rubber band ligation gr 3+4 = hemorrhoidectomy
136
describe stapled hemorrhoidectomy
less painful higher recurrence rate
137
MC location for undescended testes?
1. superficial inguinal ring 2. superficial inguinal pouch 3. ing canal
138
Tx for duo cancer at ... D1 D2 D3 D4
D1, D2: whipple D3, D4: segmental resection + LAD
139
histologic appearance of carcinoid (ie appendiceal carcinoid)
polygonal cells with granular eosinophilic cytoplasm if +mucin containing cells --> goblet cell carcinoid --> R hemi
140
indics for R hemi (appendical carcinoid)
- >2cm anywhere - any size tumor at base - HG, +margin, mesoappendiceal invasion - adenoCA - >1cm and mixed histology
141
when tx varices *non sel BB *endoscopic band ligation
large (>5mm) small (<5mm) with red spots
142
how define clinical signif portal HTN?
hepatic venous pressure gradient >/= 10
143
for cryptorchidism, after what age do you do orchiopexy?
6 months
144
what does MMC stand for?
migrating myoelectric complex
145
can you use the following in pts with PCN allergy? ertapenem aztreonam
not really (carbapenem) yes to aztreonam (monobactam)
146
calot's triangle - boundaries?
inf: cystic duct sup: inf border of liver right: common hepatic duct contains: cystic artery
147
what are the anatomic regions of the CBD?
supraduodenal retroduo infraduo
148
how to dx pheo?
#1. plasma free metanephrines (major usefulness - exclude pheo if test results are neg) #2. if positive --> 24-hr urine collection
149
when use MIBG for pheo
suspicion for multifocal disease
150
STARVATION - talk to me
*hepatic glycogen used in in 24 hr. *at 5-7d of fasting, glucose derives from GNG *epi, cortisol, glucagon stimulate GNG *hepatic GNG precursors: **alanine**, lactate, glycerol, aa/glutamine *ketone bodies are used as primary fuel source by brain/CNS/heart - not nec as precursor for GNG
151
how dx barrett esophagus?
EGD + bx (4 quadrant bx every 1-2cm w/in barrett segment) --> must show columnar epithelium for at least 1cm in distal esoph w/ intestinal metaplasia
152
mgmt for hydrocele?
usually resolve by age 1-2 if not, ligate patent processus vaginalis (for comm)
153
components of qSOFA score?
AMS RR >/= 22 SBP < 100
153
components of qSOFA score?
AMS RR >/= 22 SBP < 100
154
difference bw cutting and coag modes
cutting: continuous, low voltage current .. concentrates energy over a small area, with rapid tissue heating coag: interrupted (modulated), high voltage current, spreads energy over larger area blend: modif of cutting -- combines cutting + coag. higher blend = more time bw current and greater coag
155
MC inherited hypercoag disorder
Factor V Leiden "activated protein C resistance" *normal: protein C inactiv Factor V (--> prevent coag cascade0 *Factor V Leiden: defective Factor V protein that is resistant to Protein C
156
at what pt would you consider surgical interv on a fistula?
~12wks (3 months) --> bowel resection + full thickness excision of fistulous tract
157
what is workup for testicular mass
scrotal US LDA, AFP, hCG if have solid mass --> staging CTs tx: redical inguinal orchiectomy
158
rank 3 imaging categories with greatest to lowest radiation exposure
nuclear imaging, cardiac stress test (not bone scan) PET CT MRI - no radiation!
159
anastomosis ... scar has reached __% strength by POD3-4
60%
160
optimal candidate for MTX, for ectopic pregnancy
- HDS - no fetal cardiac activity - hCG = 5000 - willingness to comply post-treatment
161
is blood supply (inf thyroid) to parathyroids from the medial or lateral side?
medial
162
MCC PD catheter complic's overall?
infection MC noninfectious = outflow failure ^ MCC of that = constipation
163
When can you not use Tg for surveillance after cancer resection?
if there's thyroid tissue still present (ie after lobectomy)
164
What are the 4 types of QI measurements?
outcome measure (measurement of the impact on the person; ie # ppl undergoing wrong site surgery since timeout process) implemented) process measure (measurement of the ACTIVITIES; freq of timeout done) structural measures balancing measure
165
What kind of surgery has highest rate of postop delirium?
cardiothoracic surgery (then ortho, general, vascular)
166
MC site extranodal lymphoma? RF?
stomach - gastric lymphoma immunosupp (HIV), H pylori
166
MC site extranodal lymphoma? RF?
stomach - gastric lymphoma immunosupp (HIV), H pylori
167
Energy sources - temps!
45C (113 F): collagen uncoils and may realine, allowing opposed edges to form covalent bonds + fuse 60C (140 F): irrev protein denat + coag necrosis ... blanching 80C (176 F): carbonization .. tissue dries + shrinks ... cell death not yet 100C (212 F): vaporization --> cell death 125C (257 F): complete protein+lipid oxidation --> eschar
168
order of surrogates
spouse adult child parent adult sibling
169
what is energy required during lactation?
500 cal / day
170
absolute CI to PD catheter placement
- severe protein malnutrition - loss of peritoneal function - impaired physical mental ability of pt - active abd infection - freq epi's of diverticulitis
171
what are the 4 core skills of TeamSTEPPS?
mutual support leadership communication situation monitoring
172
pts >40 yrs old with perf appy ... longterm mgmt?
colonoscopy + interval appy
173
tx for CMV
ganciclovir foscarnet cidovir
174
tx for c diff - first occurrence - fulminant
first occurence: oral fidaxomicin or oral vanco fulminant: oral vanco + iv flagyl
175
signs of air embolism?
harsh continuous murmur hypoxemia, hypercarbia fall in end tidal CO2
176
what is sensory nerve supply of epiglottis?
upper: GP nerve (GAG reflex) lower + laryngeal mucosa above vocal cords: SLN, internal branch (COUGH reflex)
177
chronic pancreatitis gastric varices no evidence of portal HTN cause?
splenic vein thrombosis "sinistral HTN" definitive mgmt: splenectomy
178
CI to hepatic resection for HCC, in setting of cirrhosis
- evidence of portal HTN (esoph varices) - thrombocytopenia signs of advanced cirrhosis ... just go to liver transplant if a candidate
179
rapid correction results in ... - hypoNa - hyperNa
hypoNa: ODS (osmotic demyelination syndrome) *cannot move extremities + dysarthria hyperNa correction: cerebral edema + brainstem herniation *decorticate/decerebrate posturing .. cheynes stoke respiration (medulla) .. death
180
rate control in pt with CHF specifically and afib?
amio
181
what are immunomodulating agents that decrease rate of infectious complications + shorter LOS
arginine omega 3 FA (ALA, DHA, EPA) nucleotides
182
when do AV sampling?
no lesions on imaging b/l lesions b/l hypertrophy
183
optimal UOP for pts <30 kg (burn)
1-2cc/hr
184
is there a difference between pylorus preserving whipple v classic whipple (w/ antrectomy) ?
no - surgeon preference
185
goal CD4 count in HIV person
>500 is pretty good <200 assoc with illnesses
186
3 causes of biliary obstruction (most common first)
gallstones malignancy inflammatory stricture (ie from pancreatitis, PSC, Mirizzi)
187
causes of AG metab acidosis
mudpiles methanol uremia dka propylene glycol Isoniazid lactic acidosis ethylene glycol salicylates
188
what PSA size do you treat, and how? what makes it complicated?
PSA <2-3cm: serial US q2 wks for 6 wk period --> if growing, sx, or fail to resolve --> need treatment PSA >2-3cm: US compression v thrombin injection Complicated = skin changes, infection, HD instability, neuro changes
189
how drain paronychia
along perionychial groove (lateral nail groove) after lifting nail plate
190
air movement with flail chest - during inspiration?
flail chest wall collapses inward, causing air to move to uninvolved side, causing mediastinal shift to uninvolved side expiration: flail segment balloons out --> air moves towards trachea/bronchi of involved side --> mediastinal shift towards involved side
191
Heat generated by ultrasonic conventional electrosurgery
ultrasonic: 50,000 Hz to cut tissue up to 200 deg C for hemostasis conventional electrosurgery: 150-400 deg C
192
cure for hep C?
sofosbuvir + ribavaran
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MC indiction for liver transplant?
HCC
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MC reason for unplanned admission after elective general surgery
PONV
195
30 day mortality rate for elective open repair of TAA is __%
10
196
inotropes of choice in cardiogenic shock?
dobutamine (unless hypotensive) dopamine
197
MC melanoma mutations
V600E BRAF
198
treatment for annular pancreas?
surgical bypass
199
unresectable metastatic melanoma
ipilimumab (+ nivo (aPD-1) if expression is positive) vemurafenib ONLY for V600E BRAF mutation specifically
200
predictors of improved pancreatic allograft fxn (4)
donor age <45 donor bmi <30 traumatic cause of death short preservation time
201
MCC lymphangitis (org) in ppl with normal immunity
Strep pyogenes
202
appendicitis signs
iliopsoas (extension of R hip) - retrocecal appendix obturator sign (internal rotation R hip) - pelvic appendix *can correlate with urinary symptoms
203
breast cancer
pts with T1-2 cancer (N0, HR+, HER2-) ---> recurrence score <10: good. >26: adj chemo
204
CI to living donor kidney DONOR
diabetes, high HTN, active cancer BMI>40 GFR<70 pelvic or horseshoe kidney signif psych impairment causing issues w consent kidney stones w high chance recurrence (struvite, cysteine)
205
how to get better visualization of inominate artery injury?
ligate inominate vein
206
how treat prolactin macroadenoma of pituitary?
medical mgmt first: cabergoline > bromocriptine (dop agonist) *trend PRL levels *repeat MRI in 6-12 months IF first medical agent ineffective - try another SURGERY: failure of med mgmt; pregnancy
207
MC location mets for CRC
1. liver 2. lung
208
what are markers of melanoma?
HMB-45 MELAN-A S100 SOX-10 MITF
209
MC fungal infection during immunosupp?
aspergillosis
210
what should AFP level be after HCC resection?
<10
211
ABSOLUTE CI to lap chole (2)
uncorrected coagulopathy inability to tolerate pneumoperitoneum