Abx

Question 1

inhibits NA synthesis

Answer 1

sulphas, trimethoprim, quinolones, nitroimidazoles

Question 2

inhibits cell wall synthesis

Answer 2

penicillins, cephalosporins, vanc

Question 3

inhibits protein synthesis

Answer 3

aminoglycosides, tetracyclines, macrolides, chloramphenicol

Question 4

suphas

Answer 4

inhibit pre-DHFR step

Question 5

trimethoprim

Answer 5

inhibits DHFR

Question 6

quinolones

Answer 6

inhibit DNA gyrase

Question 7

nitroimidazoles

Answer 7

NA analogues

Question 8

every Rx needs

Answer 8

generic drug name, dose (w/units), frequency, duration

Question 9

community acquired meningitis

Answer 9

ceftriaxone 2g IV q 12h +/- vanc 1g IV q 12h +/- ampicillin 2g IV q 4h

Question 10

brain abscess

Answer 10

ceftriaxone 2g IV q 12h +/- flagyl 500mg q 12h

Question 11

acute sinusitis

Answer 11

no Abx

Question 12

chronic sinusitis

Answer 12

TMP=SMZ DS BID x 10 days, amoxicillin/clavulanic acid 875mg VID x 10d, azithromycin, quinolone

Question 13

otitis media

Answer 13

81% improve w/o abx. if tx, consider 1x IM ceftriaxone 50mg/kg

Question 14

otitis externa

Answer 14

mild = acetic acid drops. moderate = corticosporin otic drops, severe/nonresponsive = ofloxacin or ciprofloxacin HC otic drops, malignant OE = levofloxacin 500mg q 24h

Question 15

pharyngitis bugs

Answer 15

mostly GAS, some C. diptheriae, N. gonorrheae, EBV, HIV, staph

Question 16

acute bacterial pharyngitis

Answer 16

penicillin V 250-500mg PO BID, amoxicillin 250-500mg PO BID, benzathine PCN 1.2 MU IM, azithromycin 500mg 1st dose, f/u 250mg PO x 4d

Question 17

acute bronchitis

Answer 17

NO ABX!

Question 18

chronic/COPD bronchitis

Answer 18

doxycycline 100mg BID or TMP-SMX DS BID or azithromycin 500mg x 1 then 250mg QD

Question 19

CAP: S. pneumo

Answer 19

azithromycin 500mg QD + pCN 3MU IV q4h

Question 20

CAP: mycoplasma/C. pneumo

Answer 20

azithromycin 500mg QD + dozycycline 100mg BID

Question 21

CAP: multiple lobes (as above, Legionella)

Answer 21

levofloxacin 500mg IV q24h

Question 22

aspiration pna: outpt

Answer 22

PCN 3MU IV q4h + flagyl 500mg q12h

Question 23

aspiration pna: nosocomial

Answer 23

cefipime 1g IV q12h

Question 24

simple cystitis

Answer 24

TMP-SMX DS BID x 3d

Question 25

complicated cystitis

Answer 25

Tx x 7d, quinolone (levo 250mg QD or cipro 500mg VID)

Question 26

pyelonephritis

Answer 26

Tx x 14d

Question 27

urethritis

Answer 27

Tx for chlamydia and gonorrhea: CFTX 125mg IM x 1 + azithromycin 1g PO or 100mg BID x 7d

Question 28

trichomoniasis

Answer 28

flagyl 2g PO x 1

Question 29

BV

Answer 29

flagyl 2g PO x 1

Question 30

cervicitis

Answer 30

CFTX 125mg IM + azithromycin 1g PO or 100mg BID x 7d

Question 31

PID

Answer 31

CFTX 125mg IM + azithromycin 1g PO or 100mg BID x 7

Question 32

folliculitis/furuncle

Answer 32

anti-staph agents +/- I&D

Question 33

erysipelas

Answer 33

GAS, needs empiric Abx

Question 34

intestinal infection

Answer 34

often DNR and anaerobes, needs early broad spectrum: ampicillin/sulbactam 1.5g IV q8h + flagyl 500mg VI q12h OR levo 500mg IV QD + flagyl 500mg q12h