ABX-Table 1

Question 1

Traditional Pencillins

Answer 1

gram positive infections, block cell wall production, Streptococcus coverage

Question 2

PCN tx

Answer 2

Syphilis

Question 3

Traditional PCN are

Answer 3

PCN, Ampicillin, amoxicillin

Question 4

Traditional pcn tx?

Answer 4

GBS prophylaxis in pregnant women(prevent meningitis)

Question 5

Amoxicillin covers?

Answer 5

Ear infections(children), strep throat- STREP infections

Question 6

Semi synthetic PCNs?

Answer 6

Oxacillin, Nafcillin, Dicloxacillin, Cloxacillin-

Question 7

What do semi-synthetic pcns tx?

Answer 7

STAPH- NOT MRSA

Question 8

Ampicllin tx?

Answer 8

Lyme disease

Question 9

What are the generations of cephalosporins representing?

Answer 9

1-4 generations, first and second are good for

Question 10

What do cephalosporins not cover?

Answer 10

Listeria and MRSA

Question 11

What do cephalosporins cover?

Answer 11

Ceftazidime and cefepime cover pseudomonas

Question 12

What percent cross sensitivity can be observed from ppl with a pcn allergy, when initiating a cephalosporin?

Answer 12

3-5%

Question 13

What is the 4th gen cephalosporin?

Answer 13

Cefepime

Question 14

What are the macrolides?

Answer 14

Erythromycin, azithromycin, clarithromycin

Question 15

What do you use when a pt has strep throat, but us allergic to PCN?

Answer 15

Macrolide!

Question 16

What do macrolides cover that is different from PCNs?

Answer 16

additionally covers atypicals! (ligionella, mycoplasma, mycobacteria, chlamydia, H influenzae)

Question 17

What macrolide is the drug of choice for walking pneumonia?

Answer 17

Azithromycin

Question 18

What else does azithromycin tx, usually with ceftriaxone?

Answer 18

tx. of chlymydia and gonorrhea

Question 19

What do Quinolones cover?

Answer 19

Broad spectrum, covers gram positive staph and strep AND gram negative AND atypicals! good empiric therapy for pneumonia

Question 20

What are the quinolones?

Answer 20

Levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin, quinupristin

Question 21

What are the risks of perscribing a quinolone?

Answer 21

tendon rupture, C.diff, don’t use in pregnancy, DNA gyrase formation inhibited

Question 22

Are quinolones used in UTI and prostatitis tx?

Answer 22

YES!, and intractible infectious diarrhea

Question 23

Aminoglycosides are?

Answer 23

Gentamycin, tobramycin, amikacin

Question 24

What do aminoglycosides cover?

Answer 24

Pseudomonas, listeria, and gram negatives

Question 25

AEDs of aminoglycosides?

Answer 25

ototoxicity, renal toxic, never used in pregnant women

Question 26

What is amp/gentamicin used to tx?

Answer 26

severe internal infection like endocarditis or listeris meningitis

Question 27

CF aminoglycoside used?

Answer 27

nebulized tobramycin d/t pseudomonas colinization.

Question 28

what are the Carbapenems

Answer 28

Imipenem, meropenem, ertapenem,

Question 29

What do cabapenems cover?

Answer 29

Positive, negative and anaerobics,

Question 30

what are cabapenems not effective against?

Answer 30

Atypicals

Question 31

which carbapenems are effective agains pseudomonas?

Answer 31

Imipenem, miropenem

Question 32

When are carbapenems used as DOC?

Answer 32

during febrile neurtropenia of unknown origin

Question 33

what are the tetracyclines?

Answer 33

Doxycycline, tetracycline, tigecycline

Question 34

what do tetracyclines used for?

Answer 34

Doxi against rickettsia, malaria prevention,

Question 35

Tigacycline covers what?

Answer 35

MRSA!!- usually in skin and soft tissue and intra abdominal infections

Question 36

What are the ADRs of tetracyclines?

Answer 36

don’t use in children or pregnant women- stains teeth in child

Question 37

What does vancomycin cover?

Answer 37

Gram postiive and anaerobes, C.diff and MRSA

Question 38

what is vancomycin primarily cover?

Answer 38

C.diff(IV)and MRSA

Question 39

What is the DOC for C.diff?

Answer 39

Vancomycin

Question 40

What PCN/beta lactamase combo used for pseudomonas?

Answer 40

Pipercillin/tazobactam

Question 41

What is augmentin?

Answer 41

Amoxicillin/clavulanate

Question 42

What is Zosyn?

Answer 42

pipercillin/tazobactam

Question 43

What drugs cover anaerobes?

Answer 43

Clindamycin and metronidazole

Question 44

What is used for anaerobes below the diaphram?

Answer 44

Metronidazole

Question 45

What is used for anaerobes above the diaphragm?

Answer 45

Clindamycin

Question 46

what are the adrs of clindamycin?

Answer 46

Cdiff!! big time!

Question 47

what is most commonly used for utis?

Answer 47

Trimethoprim/sulfamethozasole- not in pregnancy though

Question 48

what is rifampicin used for?

Answer 48

TB tx, prophylaxis of meningococcal meningitis and H.influ infections

Question 49

What is linezolid used for?

Answer 49

highly resistant skin infections with MRSA

Question 50

what is quinupristin/dalfopristin used for?

Answer 50

treat MRSA!!

Question 51

What drugs treat pseudomonas?

Answer 51

pipercillin/tazobactam, ceftazidime, defipime, imipenem, meropenem, gentamicin, amikacin, tobramycin, aztreonam

Question 52

what tx mrsa

Answer 52

vanco, linesolid, tigacycline, quinupristin/dalfopristin