Accessory Proteins for Actin Filaments and microtubules

Question 1

Nucleates assembly and remains associated with growing plus end (actin)

Answer 1

Formin

Actin subunit associated

Question 2

Binds to subunits, prevents assembly (actin)

Answer 2

thymosin

Actin subunit associated

Question 3

Binds ADP-actin filaments, accelerates disassembly (actin)

Answer 3

cofilin

Actin filament associated

Question 4

Filament bundling
cross-linking
attachment to membrane (actin)

Answer 4

filamin (filament bundling)
alpha actin (cross links 2 actins)
fimbrin: cross links 3 actins)
ERM (attaches to membrane)
Actin filament associated

Question 5

Stabalizes filament (actin)

Answer 5

tropomyosin

Actin filament associated

Question 6

binds to subunits, speeds assembly (actin)

Answer 6

profolin

Actin subunit associated

Question 7

Nucleates assembly to form a web and remains associated with minus end (actin)

Answer 7

ARP complex

Actin subunit associated

Question 8

MT filaments: Nucleates assembly and remains associated with the minus end

Answer 8

gamma-TuRC

Question 9

MT filaments: stablilizes plus ends and accelerates assembly

Answer 9

XMAP215

Question 10

MT filaments: stabilizing tubules by binding along sides

Answer 10

MAPs

Question 11

MT filaments: Filament bundling and cross-linking

Answer 11

MAP-2

Tau?

Question 12

MT filaments: Enhances catastrophic dissasembly at plus end

Answer 12

kinesin 13