Acid Base Balance Flashcards
1
Q
Give 3 reasons why HCO3- in the body is not depleted?
A
Kidney recovers all HCO3-
PCT makes HCO3- from amino acids
DCT makes HCO3- from CO2 and H20
2
Q
Name 2 ways HCO3- leaves the basolateral surface of the PCT?
A
AE
Na HCO3- symporter
3
Q
What 2 ions buffer H+ in the lumen?
A
NH4+ and phosphate
4
Q
What is the ONLY cause of an elevated anion gap acidosis in where NO excess pathological acids are produced?
A
Renal failure - due to phosphate, urate and sulfate
5
Q
What acid base status can not be compensated?
A
Metabolic alkalosis
6
Q
Name 3 conditions that can lead to metabolic alkalosis.
A
Vomiting Mechanical drainage of stomach blocks - HCO3- builds up Mineralacorticoid excess (potassium depletion)
7
Q
What are the 2 types of RTA
A
Type 1 - cant secrete H+
Type 2 - cant reasborb HCO3-
