ACMT Board Review Course Buzzwords Flashcards

(226 cards)

1
Q

Pneumoconiosis with hilar adenopathy, clinically and pathologically identical to sarcoidosis except no eye involvement, lymphocyte transformation test

A

Berylliosis

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2
Q

Porphyria, pemba yara, spongiform encephalopathy, outbreak in turkey in 1956

A

Hexachlorobenzene

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3
Q

Isolated thrombocytopenia, “bathtub refinished lung” sensitizing agent, largest recognized cause of occupational asthma

A

Toluene di-isocyanate

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4
Q

Hepatic angiosarcoma

A

Vinyl chloride

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5
Q

Pesticide operator with sterility, altered sex ratio in offspring

A

Dibromochloropropane (DBCP)

Da balls can’t produce

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6
Q

Phossy jaw

A

Yellow phosphorus

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7
Q

Brown lung, Monday morning tightness, byssanosis

A

Cotton

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8
Q

Hypertension, saturnine gout, renal failure, microcytic anemia

A

Adult lead poisoning

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9
Q

Silver solderers, proximal RTA, Itai-itai disease in jintsu river basin, acute lung injury, renal failure

A

Cadmium

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10
Q

Perforated nasal septum, lung cancer, painless ulcers, “blackjack disease”, type 4 hypersensitivity dermatitis

A

Chromium

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11
Q

Hairdresser with hearing loss renal failure, methemoglobinemia

A

Bromate

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12
Q

A cute psychosis with elevated chloride level

A

Bromide

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13
Q

Solvent, epoxide metabolite, degreasers flush, trigeminal neuralgia

A

Trichloroethylene

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14
Q

Viscous rayon, increase rate of atherosclerosis, disulfiram and metam sodium metabolites, basal ganglia toxin, associated with spontaneous abortions, decreased spermatogenesis, craniofacial abnormalities, optic nerve and retinal degeneration

A

Carbon disulfide

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15
Q

The percentage of sick people who are identified as having the condition

Or

The likelihood of a test being positive if the condition is present

A

Sensitivity

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16
Q

A result of 100% means that the test recognizes all healthy people as healthy

Or

The likelihood of the unaffected individuals correcting having a negative test

A

Specificity

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17
Q

Solvent, acute can depression, arrhythmias, aml, Hodgkin’s lymphoma, paroxysmal nocturnal hemoglobinuria

A

Benzene

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18
Q

Wastewater treatment worker with sensory and motor distal axonal neuropathy , also has blue discoloration of hands and feet, desquamation and pulmonary irritation

A

Acrylamide

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19
Q

Ginger Jake, NTE inhibitor, sensory motor neuropathy, -1960 Morocco disaster

A

Triorthocresylphosphate

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20
Q

Mina mats bay

A

Methyl Mercury

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21
Q

Bhopal diasaster

A

Methyl isocyanate

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22
Q

Lung cancer, beer drinker with cardiomyopathy, classic tetrad

  1. Goiter
  2. Cardiomyopathy
  3. Metabolic acidosis
  4. Polycythemia

Inhibits oxidation of a-KG 59 succinyl-Co-A and pyruvate to acetyl-CoA

A

Cobalt

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23
Q

Pulmonary disease-anemia syndrome

Strong respiratory sensitizer

A

Trimellitic anhydride

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24
Q

Uranium mining, lung cancer

A

Radon

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25
Firefighter with delayed pulmonary edema and smell of freshly mowed hay
Phosgene
26
Pest control operator with fishy odor, respiratory distress, refractory hypotension, delayed pulmonary edema
Phosphine AKA phosfish
27
Sewage worker with rapid collapse, mucous membranes irritation, blackened jewelry, sodium nitrite antidote
Hydrogen sulfide
28
Endoscopy technician with mucous membrane irritation, pulmonary edema, leukemia, sweet odor, N/V
Ethylene oxide
29
Epping jaundice
Methylenedianiline
30
Aromatic solvent, acute CNS depression, basal ganglia toxin, hypokalemia, pneumonitis, RTA/renal failure, myopathy, leukoencephalopathy
Toluene
31
Fungicide with pungent odor, skin and respiratory sensitizer, photoallergic dermatitis
Captafol
32
1937 sulfanilamide poisoning
Diethylene glycol
33
Neonatal gasping syndrome
Benzyl alcohol
34
1986 lake nyos disaster
Carbon dioxide
35
Eosinophilia myalgia syndrome
L-tryptophan
36
Koremlu poisoning
Thallium
37
Explosives/munitions production, spandex fibers, causes severe GI distress and vomits that smells like bitter almonds, retro ulnar and optic neuropathy, methemoglobinemia, hepatitis, aplastic anemia, yellowing of skin hair and dyes
1,3 dinitrobenzene
38
Oily liquid used in explosives and diisocyanate production, possible weight loss product, uncoupler, optic neuropathy, turns skin yellow
Dinitrotoluene
39
Sweet smelling irritant gas, insect fumigant and heat stabilizer for plastic production, delayed pulmonary toxicity
Epichlorohydrin
40
Textile finishing agent and used in the synthesis of malathion, vapors result in corneal edema, photophobia, and diplopia, chronic use associated with occupational asthma, hemolytic anemia and pulmonary hemorrhage
Maleic anhydride
41
Used as an odors t for natural gases, rotten cabbage odor, methemoglobin and hemolytic anemia
Mercaptans
42
Abdominal pain, hemolytic anemia, Paris green, hematuria, bronze skin
Arsine
43
Metals that produce non-fibrogenic benign pneumoconiosis (5)
1. Tin (stannosis) 2. Barium (baritosis) 3. Iron (siderosis) 4. Calcium (chalitosis) 5. Melybdenun
44
Vineyard sprayers lung - interstitial pulmonary fibrosis, histiocytic grabulomas, adenocarcinoma
Copper sulfate - Bordeaux solution
45
Hard metal pneumoconiosis, pulmonary eosinophilia portends poor prognosis
Tungsten-carbide
46
Diamond polishers lung
Cobalt
47
Patient on dialysis who develops somnolence, peri oral numbness, abdominal pain and hyperamylasemia
Manganese sulfate
48
Worker with osteosclerosis with accompanying nerve root compression. Plain film X-ray reveals ligament calcification and lesions resembling osteoblasts metastasis
Fluorisis cryolite (NaAlFl)
49
Acroosteolysis (bone resorption at distal phalanx)
Vinyl chloride
50
Most common medication associated with hypersensitivity pneomonitis
Nitrofurantoin
51
Middle aged adult with chronic seizure disorder with X-rays demonstrating hilar lymphadenopathy. Biopsy reveals drug-induced lymphoid hyperplasia.
Phenytoin
52
Elderly male with hepatic angiocarcinoma and pneumococcal sepsisz abdominal X-ray reveals multiplied opacities in the liver and spleen
Thorotrast (thorium dioxide)
53
Zenobiotic induced aplastic anemia is most often associated with destruction of these progenitor cells
CD34+ progenitor cells
54
Lymphoma in a Dutch flower bulb worker using a nematode fumigant (also seen in fireman)
Dichloropropene (telon)
55
Cola colored infant with MRCP, abnormal skull calcification and hypo plastic nails
PCBS PEPSI COLORED BABIES
56
Metabolite of disulfiram and used in the treatment of nickel carbonyl and platinoid poisoning
Diethylsithiocarbamate (DDC)
57
4 year old in an antineoplasric drug develops fever, SIADH, necrotic myocardial infarction, and loss of deep Tendon reflexes
Vincristine
58
Antineoplastic producing hilar adenopathy
MTX
59
Antineoplastic producing nodular bronchiolitis ollbliterans
Bleomycin
60
Antineoplastic associated with perforation of the GI tract
Paclitaxol
61
Antineoplastic associated with hemolytic uremic syndrome
Mitomycin
62
Metal that is radiolucent on plain film X-ray
Copper
63
Metal causing parasthesias (pins and needles), ataxia, dysarthria, constructed visual fields, deafness
Methyl Mercury
64
Pink disease - Mercury teething powders such as calomel
Mercury calomel (HgCl)
65
Hopewell epidemic, "Kepone shakes", Chessapeake Bay contamination
Chlordecone
66
Stalinon poisoning, vomiting, transitory paralysis, photophobia, white matter edema
Triethyltin
67
Golfer with disulfiram reaction at the 18th hole
Thiuram Herbicide
68
Welder with early Parkinson's Disease
Manganese
69
Paraket dies while family is cooking in the kitchen
Polymer fume fever
70
Welder dies after ingesting soldering flux
Zinc chloride
71
Black henna, black hair dye, angioedema, renal failure, methemoglobinemia, leukemia/bladder cancer
Para-phenylenediamides
72
Fumigant worker, peanut poisoning, fish odor
Zinc phosphide
73
Young male chimney sweeper with testicular cancer
Polyaromatic hydrocarbons
74
Middle aged male stripping paint that develops angina from delayed carbon monoxide poisoning
methylene chloride
75
Galvanized metal welder, "Monday morning fever", "brass foundry workers argue"
Zinc oxide (metal fume fever)
76
Mill worker with allergic contact dermatitis, and respiratory sensitization (occupational asthma)
Plicatic acid (western red cedar)
77
Farmer's lung
Thermophilic actinomycetes
78
irritant gas, warning agent in methylene chloride, component of papite (tear gas), cyclophosphamide metabolite
Acrolein
79
Urine metabolite of acrylamide used for testing worker exposure
carboxyethyl-cystine
80
Primary ingrediant in skin cement, skin sensitizer, elevated urine mercapturic acid, pediatric burns
methyl methacrylate
81
Spain 1981: rapeseed oil contaminated with aniline, diffuse pulmonary infiltrates on x-ray, methemoglobinemia
aniline
82
Airbag inflation, herbicide, cytochroma alpha-a3 inhibitor
sodium azide
83
Fumigant, fire extinguisher, lower extremity axonopathy, intoxication resemble's Wernicke's encephalopathy, inferior colliculi lesions, NAC may worsen syndrome
Methyl bromide
84
Irritant gas with gasoline-like odor, may cause hypotension and bradycardia with inhalation, associated with lymphohematopoetic cancer
1, 3, butadiene
85
Current pesticide/herbicide but once a mouthwash and toothpaste, methemoglobinemia and Gi distress 3-6 hours after ingestion
sodium chlorate
86
Hyperthyroid medication that was linked to aplastic anemia, now ground water contaminant
Perchlorates
87
Tar smarts, pitch warts and squamous cell carcinoma, chronic melanosis, UV phototoxicity, strong carcinogen of lung, bladder, skin, scrotal, oral, stomach
Coal tar products
88
Ammonia-like odor, rocket fuel and water treatment agent: toxicity tetrad: SLE (skin sensitizer), methemoglobinemia, seizures, hepatitis
Hydrazines
89
Paint remover and solvent with fishy or ammonia smell that cause severe hepatitis with jaundice and eventual liver failure
Dimethylacetamide
90
Solvent used in pharmaceutical industry, acrylic fiber production and recovery of CO2 in gasses that may result in skin irritation, severe hepatotoxicity, and disulfiram reactions
N,N-dimethylformamide
91
Riboflavin inhibition, painful peripheral neuropathy, neuropathy spares CN 1, 5, 8, slope is with sparing of the Axila facial hair and inner 1/3 of eyebrow, reverse sleep cycle
Thallium
92
Benzene monitoring
Total urine phenol
93
Toluene monitoring
Urine hippuric acid
94
Styrene monitoring
Urine mandelic and phenylglyoxylic acid
95
Lead monitoring
Blood ZPP/FEP
96
Methyl Mercury monitoring
Blood Mercury
97
Inorganic Mercury monitoring
Urine Mercury
98
Polyaromatic HC monitoring
Urine 1-hydroxypyrene
99
Pily liquor in cold sterilization, sensitizer and occupational asthma
Glutaraldehyde
100
Used in plastics and rubber, dental fillings and styrofoam. Causes flu-like symptoms and drunkenness activity, peripheral neuropathy and hearing loss chronically
Styrene - styrene syndrome
101
Chemical associated with highest incidence of lung cancer in the world
Polyaromatic HC
102
Dentist with vitamin b-12 like deficiency, bone marrow suppression, and pernicious anemia. Histochemistry reveals inactive cobalt and inhibition of methionine synthetase.
Nitrous oxide
103
Person exposed to a cloud of “red smoke” with delayed pulmonary edema and chemical burns with characteristic yellow discoloration
Nitric acid
104
Pyrophoric material causing severe thermal and chemical burns (submerge in CuSO4) and exposure may lead to hepatotoxicity and hypocalcemia and increase QT interval
White phosphorus
105
“Rush” fire in San Fran in 1983 leading to a number of firefighters with methemoglobinemia
Isobutyl nitrate
106
1978 Jonestown mass suicide
KCN
107
Only organic phosphorus pesticide that possesses a significant vapor hazard (high vapor pressure)
Dichlorvos (also very hydrophilic - amenable to HD maybe)
108
Patient presenting after herbicide ingestion with myotonia, myoclonus, hematuria/rhabdo, and cardiac disturbances
Chlorphenoxy herbicide
109
Fetal syndrome - 10-30%, 25% risk of spontaneous abortion, microcephaly/hydrocephaly, conventional heard disorders, microtia, cleft lip-palate
Fetal isotretinoin
110
Microcephaly, development delay, telecsnthus, short nose and flat nasal bridge, anteverted nares, long shallow fitrum, thin upper lip, nail displasia
Fetal hydantoin
111
Microcephaly, small palpebral fissure length, thin upper lip, smooth Phil trim, flattened cheeks and short nose. Risk of brain injury increases as eyes get smaller, philtrum get flatter, and lip gets thinner
Fetal alcohol
112
Small nose and markedly depressed nasal bridge, brachydactyl, hypoplasia of all distal phalanges, severe shortening of lower extremities, epiphyseal stippling of the sacrum, spine, proximal humeri, and femurs
Fetal warfarin
113
Parrot fish and tidal xanthid crabs | Inhibits Na/K ATPase, N/V/D, parasthesias, hypocalcemic tenany, CV collapse (second most potent toxin on earth)
Palytoxin
114
Paralytic shellfish poisoning, Na channel blocker, oysters/red tide, N/V, parasthesias, throat pain, descending paralysis
Saxitoxin
115
Neurotoxin shellfish poisoning, sodium channel opener, parasthesias, temperature reversal, N/V/D uncommon, tide aerosolized toxin causes conjunctivitis, rhinitis, bronchitis
Brevetoxin
116
Diarrhetic shellfish poisoning, inhibits protein phosphates disrupting cell metabolism, benign gastric tumors, N/V/D predominate
Okadaic acid
117
Amnestic shellfish poisoning, CNS glutamate receptor stimulation causing Na channel up regulation and Na/Ca influx g neuronal cell dementia, N/V/D, headaches, ataxia, seizures, associated with eating blue muscles
Domoic acid
118
Na and Ava channel opening, metallic taste, parasthesias, glove and stocking numbness, hot/cold reversal, sensation of loose teeth, symptoms worse with alcohol
Ciguatoxin
119
Bacteria-catalyzed decarboxylation of decomposition finfish muscle, sunburn like rash, urticaria, bronchospasm
Scombroid (histamine poisoning)
120
Sodium channel blocker, perioral parasthesias, numbensss tremor ataxia dysarthria dysphasia respiratory paralysis death 5th most potent toxin
Tetrodotoxin
121
Japanese vinyl sandal maker with peripheral sensorimotor neuropathy. Nerve biopsy reveals Axonal swelling.
N-hexane
122
Cicuta spp. Most fatal plant species in North America - 30-70% fatality rate
Water hemlock -
123
The only form of poisoning caused by bacterial contamination
Scombroid (decarboxylation of histadine in fish muscle to histamine)
124
St Anthony’s fire, ergotism
Claviceps purpurea
125
Structural similarity to the herbicide endothall, also known as Spanish fly, produced by the blister beetle
Cantharidin
126
Profound hypoglycemia, hepatitis with hyperbilirubinemia, acid emus and acidurea without Ketosis
Akee (hypoglycin)
127
The maximum concentration of a chemical to which a worker may be exposed continuously for up to 15 minutes without danger to health or work efficiency and safety
Stel - short term exposure limit
128
Sulfonylurea known to cause SIADH and disulfiram reactions
Chlorpropamide
129
Side chain of cephalosporins linked to disulfiram reactions
NMTT - n-methtltetrathiol
130
Antidysrhthmic with antimuscarnic properties and causes hypoglycemia
Disopyramide
131
Intoxicants that produce metaphyseal bands on plain fil x-ray
Lead Yellow phosphorus Bismuth Hyper vitaminosis D
132
5 most common medications linked to lupus-like syndrome
``` CHIMP chlorpropamide Hydralazine INH Methyldopa Procainamide ```
133
Idiopathic intracranial hypertension (pseudo tumor cerebri)
Vitamin A
134
Chinese herbal remedy with bufadenalide cardiac steroid
Chan Su
135
Plant that is a cyp3A4 inducer
At John wort - hypericum perforatum
136
Pulegone -> methofuran -> hepatitis
Pennyroyal oil (mentha pelugium)
137
Aspiration pneumonitis, CNS depression, patients urine smells like violets
Terpentine (pine oil)
138
Essential oil, CNS depression, mild hepatitis, hemorrhagic pulmonary edema
Oil of cloves - eugenol - Eugenia aromatica
139
Most common cause of medication-induced contact dermatitis
Neomycin
140
Endocarditis and mistrial vale fibrosis, pulmonary hypertension
Fenfluramine
141
Disinfectant associated with neonatal vacuoles encephalopathy and cerebral edema
Hexachloraphene
142
Disinfectant ingestion causingetahilic acidemia due to a decreased renal clearance of H (patient has normal lactate)
Providine iodine
143
Disinfectant, hypopigmented skin, TD-like syndrome, bradycardia, hypotension, PEG decontamination
Phenol
144
Rose eye discoloration of eyelids, conjunctivitis, refractory hypotension, reddish discoloration of viscera post-Mortem
Acute selenium toxicity (selenious acid)
145
Peanut worker who develops liver cancer (hepatoma)
Alfatoxin
146
Bio marker for benzene exposure
Urine phenol
147
HIV medication associated with fatal hypersensitivity
Abacavir
148
Two P450s associated with development of cancer
1A2, 2E1
149
Enzyme linked to aromatic anticonvulsant hypersensitivity syndrome
Epoxide hydrolase
150
The only medication induced seizure that will likely respond to phenytoin
Aminopyridine
151
The only local anesthetic that causes vasoconstriction
Cocaine
152
Most cardio toxic amide local anesthetic (may cause cardio toxicity before CNS toxicity
Bupivacaine
153
Most extensively metabolized anesthetic, hepatitis, malignant hyperthermia, acute lung injury from abuse (PO/IV)
Halothane
154
The only IARC Group 4 drug - probably not carcinogenic to humans
Caprolactam
155
Patient with ventricular ectopy, blindness, NV, dishonored is tinnitus after drinking tonic water with Cinchona succirubra extract
Quinine
156
Biventricular tachycardia
Digoxin, aconitine, halogenated hydrocarbons
157
Patient with an aortic dissection and renal failure that develops altered mental status, seizures, and no metabolic acidosis
Thiocyanate toxicity
158
Opioid linked to serotonin syndrome, seizures, MPTP, and may not result in milieus in overdose
Meperidine
159
NSAID linked to aplastic anemia
Phenylbutazone
160
Patient with hiv with sulfa allergy who develops hemolysis and methemoglobinemia
Dapsone
161
Patient undergoing elective endoscopy that develops methemoglobinemia during pre-op
Benzocaine
162
Free radical induced cardiomyopathy with irreversible heart failure
Doxorubicin
163
Alkylation agent causing hemmhoragic cystitis, MESNA antidote
Cyclophosphamide
164
Allylating agent causing pulmonary fibrosis and skin hyperpigmentation
Busulfan
165
6 intoxicants for which urine alkalinizarion enhances drug elimination
``` Salicylate Phenobarbital chlorphenoxy herbicides Methotrexate Chlorpropamide Fluoride ```
166
Scleritis and uveitis in a patient being treated for hypercalcemia
Bisphosphanates
167
Peliosis hepatitis
Alkalated anabolic steroids
168
Black widow spider Painful bite Calcium channel opener Causes release of NE ACH
Latrodectus mactans
169
``` Brown recluse Painless bite sphingomyelinase D Hyaluronidase Local wound (red white blue) ```
Loxosceles reclusa
170
Hobo spider Painless bite Local ulcer
Tegenaria agrestis
171
Box jellyfish Most lethal cnideria Rapid death in minutes Acetic acid/Antivenom
Chironex fleckeri
172
Irukanji syndrome Hypertension Back spasms
Carukia barnesi
173
Portuguese man of war Painful linear welts Acetic acid
Physalia physallis
174
Crown of thorns Pain, paralysis Hot water immersion
Acanthaster planc
175
Lion fish Pain possible blisters Hot water immersion
Pterosis species
176
Stonefish Cytotoxic, hemolytic, myotoxic Severe pain, hypotension, hemolysis Hot water, antivenin
Synanceja verrucosa | S. Horrida
177
Stingray Local pain Vibrio infections Hot water, antibiotics
Dasyatis species
178
Funnel web spider Massive release of ACH, NE, EPI RAbbit igg antivenin Death historically in peds under 4
Atrax robustus
179
Fire ant Glucosaminidase, piperidines Wheals, clear vesicles Local care
Solenopsis invecta
180
Bark scorpion Sodium channel opener Pain, parenthesis, palsies
Centruroidea exilicauda
181
Colorado river toad Bufadienolide cardiac steroid Bufotenin tryptamines Chan su herbal
Bufo alvarius
182
Body builder presenting with tachycardia, wide pulse pressure, hypokalemia
Clenbuterol
183
silo filers disease
Nitric oxides (No, No2)
184
Basal ganglia toxins
``` CO CArbon disulfide manganese MTPP+ Methanol ```
185
Remediation level for home radon
11 pc/L
186
Theee agents associated with perinatal death
ACE inhibitors Cigarette smoking Lead
187
Most common hydrocarbon used in dry cleaning
PERC | perchloroethylene
188
Cement worker with contact dermatitis
Chromium 6
189
OSHA PEL for benzene
1 ppm
190
OSHA PEL for CO
50 ppm
191
Azo dye and rubber manufacturing, HCN lab detection agent, methemoglobinemia, associated with bladder cancer (IARC 1)
Benzidine
192
Patient etching glass and wheel cleaning with delayed pain out of proportion to exam, hypocalcemia, hyperkalemia
HF
193
Vitamin B6 antidote for 4 toxins
INH Gyromitra esculenta Hydrazines Ethylene glycol
194
The factor by which exposure is reduced by use of a respirator
Protection factor | Ambient/protection factor = exposure
195
Study design comparing an exposed group to an unexposed group either retro-or prospectively with results expressed as relative risk
Cohort study
196
Study design comparing an exposed group to an unexposed group at one point in time. Provides prevalence data, results expressed as relative risk
Cross-sectional study
197
Study design comparing individuals with a specific condition to those do not have the condition and compare exposures or risk factors. Results expressed as odds ratio.
Case control study
198
Federal agency responsible for conducting research and making recommendations for the prevention of work related injury and illness - has no legal authority
NIOSH
199
The main federal agency charged with enforcement of safety and health legislation
OSHA
200
Enacted by Congress in 1980 and created a tax on the chemical and petroleum industries and provided broad federal authority to respond directly to releases or threatened releases of hazardous substances that may endanger public health or the environment
CERCLA | comprehensive environmental response, compensation, and liability act
201
Federal public agency charged with the responsibility of evaluating the human health effects of exposure to hazardous substances
ATSDR
202
Characteristics of substances partitioning into breast milk
low molecular weight Non-polar Low protein binding
203
Risk factors for quinolone induced tendinopathy
``` Age over 60 Non-obese Steroid use Female Renal failure Diabetes ```
204
Hepatic zone where 2E1 is primarily present and active
Zone 3 | Centeilobular necrosis
205
Primary toxicity associated with methoxyflurane
Nephrotoxicity
206
Tetrodotoxin MOA
NA channel blocker
207
Saxitoxin MOA
Blocks Na channel
208
Brevetoxin MOA
stimulates Na Channels
209
Domoic acid MOA
glutamate agonist, analog of glutamic and kainic acid
210
Okadoic acid MOA
Phosphates a1 and a1 inhibitor
211
Ciguatoxin MOA
Lowers threshold for opening Na channels
212
Toxins associated with peripheral neuropathy (5)
``` Acrylamide Methyl bromide Carbon disulfide Styrene Trichloroethylene ```
213
Occupational intoxicants associated with asthma (5)
``` Maleic acid Trimellitic anhydride Ethtlenediamine Toluene diisocyanate (#1) Diethtlhexyl phthalate ```
214
Rodenticide producing nausea vomiting bradycardia hyperkalemia
Red squill (digoxin)
215
Rodenticide producing CNS excitation, irritability, seizures, coma, ventricular dysrhythmias
Tetramine
216
Rodenticide producing orophyngeal and skin burns, smoking coming and stools, garlic odor, GI and hepatic injury
Phosphorus
217
Rodenticide producing tremors, myoclonus, depressed mental status
Bromethalin
218
Toxin used in hospital laundry. Toxicity resulted in 9 neonates ill, 2 deaths. Presented with fever sweating renal failure and acidosis, this agent was also used in various ways including in treating wood to function as preservative, also uncouples oxidative phosphorylation
Pentachlorophenol
219
Chemicals associated with causing chloracne
Chlorinated aromatic hydrocarbons
220
Hairdresser hand dermatitis
P-phenylenediamine
221
International treaty completed in 1987 by 24 nations to control the depletion of the ozone layer. Targeted the decrease of CFCs and halons used in fire extinguishers - halon 1211 and 1301
Montreal protocol
222
Shoemakers polyneuropathy
N-hexane... same as with methy-n-buyl ketone. All metabolized to 2,5-butanedione
223
Toluene toxicity (4 major)
Distal RTA MEtabolic acidosis Hypokalemia and associated symptoms Leukoencephalopathy
224
The only hydrocarbon exposures associated with a chance in CV mortality
Carbon disulfide Associated with accelerated atherosclerotic CAD ALso peripheral neuropathy
225
Cement eczema
Chromium 6+ | Type 4 hypersensitivity reaction
226
Wolf-chaikoff effect
Chronic iodine exposure leads to decreased hormone productions the inhibition of organic binding of iodide in the thyroid gland by excess iodide leading to decreased thyroid synthesis