Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Acne Treatment > Acne > Flashcards

Acne Flashcards

Epidemiology (61 cards)

Start Studying
1
Q

What is the resolution process for infant acne?

A

Resolution occurs without treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How is childhood acne treated?

A

Treatment is similar to adults; start with low concentrations and reserve systemic options

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which antibiotic is recommended instead of tetracyclines for children under 9 years old?

A

Erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What complication is associated with isotretinoin in children?

A

Early closure of epiphyseal plates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is a key consideration for treating acne in pregnancy?

A

Many therapies are teratogenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which topical antibiotics are good options for pregnancy acne?

A
  • Erythromycin (oral and topical)
  • Clindamycin (topical)
  • Azelaic acid (topical)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does ‘non-comedogenic’ refer to?

A

Water-based vehicles free of substances known to induce comedones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What type of products should patients with oily skin look for?

A

Solutions/gel that are more alcohol/drying

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is a pledget?

A

A single-use medication-containing pad

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the mechanism of action for Benzoyl Peroxide?

A

Antimicrobial agent that releases free oxygen radicals and is mildly comedolytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the concentration range for Benzoyl Peroxide?

A

2.5-10%; lower concentrations are better tolerated but less effective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the first topical retinoid?

A

Retinoic Acid (Tretinoin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the main use of topical retinoids?

A

Comedolytic, anti-inflammatory, improves dyspigmentation, maintains clear skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the recommended treatment for mild acne?

A

Topical benzoyl peroxide (T BP) or topical retinoid (T Ret)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What should be combined with topical antibiotics?

A

Another agent such as benzoyl peroxide (BP) or retinoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the primary adverse effect of Isotretinoin?

A

Teratogenic effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the iPledge program associated with?

A

Management and prevention of pregnancy in patients taking Isotretinoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the mechanism of action for spironolactone?

A

Androgen receptor antagonist that reduces sebum excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the primary first-line systemic antibiotic for moderate to severe acne?

A

Doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the main benefit of using Combination Oral Contraceptives (COCs) for acne?

A

Reduces ovarian androgen production to decrease sebum production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is Clascoterone’s mechanism of action?

A

Androgen receptor antagonist that inhibits androgen-mediated lipid and inflammatory cytokine synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the common adverse effect of topical dapsone?

A

Dryness, peeling, redness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Which topical agent is known for promoting epidermal shedding?

A

Salicylic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is the recommended duration for systemic antibiotics in acne treatment?

A

Limited to 3-4 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is the mechanism of action of retinoids?
Targets retinoic acid receptors and alters cell differentiation
26
What should be avoided when treating acne in pregnancy?
Topical and oral retinoids, tetracyclines, and antiandrogens
27
What is the effect of benzoyl peroxide on C. acnes?
Decreases aerobic bacteria by 84%, anaerobic by 98%
28
What is the effect of combining benzoyl peroxide with topical retinoids?
Benzoyl peroxide renders tretinoin unstable
29
What is the recommended application timing for benzoyl peroxide and tretinoin?
Apply BP in the morning and tretinoin in the evening
30
What is the primary consideration for topical antibiotics?
They must be used in combination with another agent
31
What is the significance of using multiple agents with different mechanisms of action?
Improves treatment efficacy and minimizes resistance
32
What is acne?
Common inflammatory skin condition characterized by chronic or recurrent development of papules, pustules, or nodules.
33
What are the main types of acne?
Types include comedonal acne, papulopustular acne, nodular acne, and conglobate acne.
34
What is the lifetime prevalence of acne?
Approximately 90%.
35
Which demographic is most affected by acne?
Affects ~80% of people between puberty and 30 years old.
36
What are the four major etiologic factors involved in the development of acne?
* Increased sebum production by sebaceous glands * Follicular hyperkeratinization * Colonization with Cutibacterium acnes * Inflammation
37
What is the role of androgens in acne?
Androgens increase sebum production in sebaceous glands, providing a growth medium for C. acnes.
38
What is the recommended first-line oral antibiotic for acne treatment?
Doxycycline.
39
What is a second-line treatment option for acne?
Sarecycline, which is weight-based dosed and has low adverse effects.
40
What should be done to minimize the risk of esophagitis when taking tetracyclines?
Take with a full glass of water and remain upright for 30 minutes.
41
What are some non-pharmacologic treatments for acne?
* Eliminate aggravating factors * Maintain a balanced, low-glycemic index diet * Control stress * Cleanse twice daily with mild soap * Use only oil-free cosmetics * Shave infrequently
42
What are the exclusions to self-treatment for acne?
* Moderate-Severe acne (types 3 and 4) * Exacerbating factors present * Pregnancy * Rosacea
43
What is the recommended duration for using oral antibiotics in acne treatment?
Limit use to 3-4 months total.
44
What are the common side effects of doxycycline?
* Photosensitivity * Nausea * Vomiting * Diarrhea * Intracranial hypertension
45
What is the mechanism of action for isotretinoin?
Targets all four pathogenic factors: antibacterial, anti-inflammatory, normalizes keratinization, and is anti-comedogenic.
46
What should be monitored during isotretinoin therapy?
* Lipids * Liver function tests * Pregnancy tests
47
What are the signs and symptoms of drug-induced acne?
Inflamed lesions with no evidence of comedones.
48
Fill in the blank: The bacterium involved in acne is called _______.
Cutibacterium acnes
49
What dietary factors are controversially linked to acne?
* Milk * Saturated fatty acids * Whey protein supplements * High glycemic load
50
What is the typical acne lesion distribution in young adolescents?
Typically comedonal acne on the forehead, nose, and chin (T-zone).
51
What is the severity grading taxonomy for acne according to the FDA?
* Type 1: Almost clear * Type 2: Mild * Type 3: Moderate * Type 4: Severe
52
What is the recommended dosing for oral isotretinoin?
0.5-2mg/kg/d over ~20 weeks; total cumulative dose ~120-150mg/kg.
53
True or False: All tetracyclines are contraindicated in pregnancy.
True.
54
What are the adverse effects of isotretinoin?
* Dry eyes * Dry mouth * Myalgia * Headache * Depression/suicidal ideation
55
What is the typical appearance of a closed comedone?
Non-inflammatory, 1-2mm, dome-shaped, smooth, skin-colored, whitish or grayish.
56
What is the common treatment approach once acne control is achieved?
Simplify the regimen using the fewest agents at the lowest dosages.
57
What are some physical modalities mentioned for acne treatment?
* Extraction * Chemical peels * Laser and light devices * Microneedling
58
Fill in the blank: The characteristic feature of papulopustular acne is _______.
Inflamed, relatively superficial papules and pustules.
59
What is the effect of high glycemic load on acne?
Increased acne.
60
What should be avoided when taking isotretinoin?
Supplemental Vitamin A.
61
Fill in the blank: The recommended duration for continuing therapy for acne is _______.
More than 8 weeks.

Acne Treatment (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions