Acromegaly & Gigantism - Disease of the Pituitary Syndrome Flashcards

1
Q

A 45-year-old man presents to his general practitioner with excessive sweating, soft-tissue swelling and pains in his hips and knees. He has also been experiencing headaches over the past few weeks. His wife reports that he has started snoring over a similar period. He has no significant past medical history. On examination, his facial features are coarse and he has prominent supra-orbital ridges. Prognathism is also evident, as well as an enlarged tongue. The fingers appear thickened.

What does he have?

A

Agromegaly

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2
Q

For Agromegaly

Which of the following is the best definitive test to confirm the likely underlying diagnosis?

A

Oral glucose tolerance test

after igf1

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3
Q

first-line test for acromegaly

A

Serum IGF-1 levels are now the first-line test for acromegaly

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4
Q

headache, sweating and visual problems. He mentions that he has noticed a change in his appearance compared with old photos and that his wedding ring no longer fits.

A

acromegaly

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5
Q

hormone that causes acromegaly

A

growth hormone

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