ACS pt5 Flashcards

1
Q

What are the long term goals of ACS therapy?

A
  • Control CAD risk factors
  • Prevent MACE
  • Improve QOL
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2
Q

When should BBs be initiated in ACS?

A

Within first 24 hours of ACS

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3
Q

What are reasons to not start a BB in ACS?

A
  • Bradycardia
  • HF
  • Risk for cardiogenic shock
  • Uncontrolled asthma or reactive airway disease
  • 2nd or 3rd degree heart block
  • PR interval >0.24 seconds
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4
Q

What should be done in pts that have initial CI to BBs?

A

Re-evaluate to determine eligibility

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5
Q

What is the starting dose of metoprolol tartrate?

A

25-50 mg q6-12h

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6
Q

What is the target dose of metoprolol?

A
  • 100mg BID w tartrate
  • 200 mg daily w succinate
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7
Q

What is the starting dose of carvedilol?

A

6.25 mg BID

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8
Q

What is the target dose of carvedilol?

A

25 mg BID

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9
Q

What is the starting dose of propranolol?

A

40 mg BID-TID

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10
Q

What is the target dose of propranolol?

A

80 mg QID

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11
Q

What is the starting dose of atenolol?

A

25-50 mg daily

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12
Q

What is the target dose of atenolol?

A

100 mg daily

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13
Q

Which BBs should be used in pts w HFrEF?

A

SR metoprolol succinate, carvedilol, bisoprolol

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14
Q

When should IV BB be considered?

A

Hypertensive or ongoing ischemia

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15
Q

When using IV BB, which BB, strength, and frequency should be used?

A

Metoprolol tartrate 5 mg IV q5min (up to 3 doses)

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16
Q

What happens when a cocaine user uses while on BB?

A

Allows cocaine to stimulate alpha receptors, possibly leading to:
- Hypertensive complications or increased troponin

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17
Q

Is it ok to give a BB to a pt w cocaine use hx?

A

Use a nonselective BB + make sure there is no cocaine in pt’s system

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18
Q

Should BBs be started or dose be adjusted during acute HF exacerbation?

A

Avoid starting or increasing BBs

19
Q

Why are BBs avoided in HF that’s not stable?

A
  • BBs can slow down heart and decrease cardiac output
  • Starting/increasing BBs during exacerbation can cause pulmonary edema
20
Q

Is it safe to continue a pt on their maintenance BBs?

A

Yes, if pt has ALREADY been on BBs:
- Continue at home dose, but do not increase until euvolemic

21
Q

What are HR and BP “hold orders” for BBs?

A
  • HR <50 bpm
  • BP <90/60
22
Q

When are CCBs given?

A

Non-DHP CCBs are given to pts w recurrent ischemia and CI to BBs

23
Q

When should CCBs not used?

A

Do not use in pts w:
- LV dysfunction (aka HFrEF)
- Increased risk for cardiogenic shock
- PR interval >0.24 seconds
- 2nd or 3rd degree AV block w/o pacemaker

24
Q

What are the high intensity statins?

A
  • Atorvastatin 40-80 mg daily
  • Rosuvastatin 20-40 mg daily
25
What is the starting dose of captopril?
6.25-12.5 mg TID
26
What is the target dose of captopril?
25-50 mg TID
27
What is the starting dose of lisinopril?
2.5-5 mg daily
28
What is the target dose of lisinopril?
>= 10 mg daily
29
What is the starting dose of ramipril?
2.5 mg bid
30
What is the target dose of ramipril?
5 mg bid
31
What is the starting dose of trandolapril (Mavik)?
0.5 mg daily
32
What is the target dose of trandolapril?
4 mg daily
33
What is the starting dose of valsartan?
20 mg bid
34
What is the target dose of valsartan (Diovan)?
160 mg bid
35
When is an ACEi not used?
- Hypotension/shock - Unilateral/bilateral renal artery stenosis - Hx of worsening renal function on ACEi/ARB - Acute renal failure - Drug allergy/angioedema
36
What are the monitoring parameters of ACEi?
- SCr (increase) - K (increase) - BP (decrease) - Angioedema
37
Why must SCr be monitored w ACEi?
- Causes an initial increase in SCr - Initial SCr increase of up to 30% is ok; d/c ACEi if initial increase >30%
38
Why does ACEi initially increase SCr?
ACEi causes efferent arteriole vasodilation
39
Which pts require oral anticoag in addition to DAPT?
- Pts w afib (CHADSVASc >=2) - STEMI and asymptomatic LV mural thrombi - STEMI and anterior apical akinesis or dyskinesis (abnormal heart wall mvnt)
40
How long should triple antithrombotic therapy last after ACS?
Duration should be minimized
41
What should be done w ASA in pts on triple antithrombotic therapy + afib?
D/c ASA after 1-4 weeks after PCI and continue P2Y12i and anticoag (NOAC > warfarin)
42
What prn NTG should be given to ACS pts?
0.3-0.4 mg SL NTG q5min for chest pain
43
What are ways to prevent recurrent MI?
- Stop smoking - Adherence to meds - Control BP - Healthy diet and exercise