Activating receptors Flashcards
1
Q
CD16 (FcyRIII)
A
H,M. Ligand: Immune complexes, Motif: ITAM/FcyR
2
Q
CD25 (IL-2Ralpha)
A
H, Ligand: IL-2
3
Q
CD27
A
H,M. Ligand: CD70, Motif: TRAF
4
Q
CD28
A
H,M. Ligand:CD80/CD86, Motif: YXXM/PI3K
5
Q
CD69
A
H,M. ?
6
Q
CD94/NKG2C,E
A
H,M. Ligand:HLA-E (H), Qa-1b (M)
7
Q
CD122 (IL-2Rbeta)
A
H,M. Ligand: IL-2, IL-15, Motif: JAK1,3/STAT5a, 5b
8
Q
CD161
A
H,M. Ligand: Clr-g (NKR-P1F)
9
Q
CD226 (DNAM-1)
A
H, Ligand: CD112 (Nectin-2), CD155
10
Q
CD244 (2B4)
A
H,M. Ligand: CD48
11
Q
NKG2D
A
H,M. Ligand: MICA, MICB, ULBs (H), RAE-1s (H,M), H60 (M)
12
Q
KIR2S, KIR3S
A
H, Ligand: HLA class 1, Motif: ITAM/DAP12
13
Q
Ly49D,H,P
A
M, ligand: H-2 class 1, MCMV m157 (Ly49H)
14
Q
NCR (NKp30, 44, 46)
A
H,M (NKp46). Ligand: ?, Motif: ITAM/FcyR, CD3-zeta chain (H), DAP12
15
Q
ILT-1 (Ig-like transcript 1)
A
H, Ligand: ?, Motif: ITAM/FcyR DAP12
